Journal
ANNALS OF TRANSLATIONAL MEDICINE
Volume 7, Issue 18, Pages -Publisher
AME PUBL CO
DOI: 10.21037/atm.2019.08.37
Keywords
Immunomodulating; long non-coding RNA (lncRNA); gene expression; epigenetics
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Funding
- National Natural Science Foundation of China [81771618]
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Long non-coding RNAs (lncRNAs) have been key regulators of gene expression in innate and adaptive immunity. Although lncRNAs have been reported to be associated with some diseases, its expression and function in diseases related to inflammation and immunity are still unknown. We reviewed how lncRNA regulated transcription and controlled the function and balance of the cells in the immune response. In addition, we discussed the impacts and challenges of lncRNAs on immunity in diseases.
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