Journal
PHOTOACOUSTICS
Volume 15, Issue -, Pages -Publisher
ELSEVIER GMBH
DOI: 10.1016/j.pacs.2019.100138
Keywords
Photoacoustic imaging; Ultrasound imaging; Endoscopic imaging; Gastrointestinal; Ultrasonic transducer; PMN-PT epoxy 1-3 composite; Composite based ultrasonic transducer
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Funding
- National Institutes of Health [R01HL-125084, R01HL-127271, R01EY-026091, R01EY-028662]
- American Heart Association [18PRE34050021]
- National Science Foundation [DGE-1839285]
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Endoscopic dual-modality photoacoustic (PA) and ultrasound (US) imaging has the capability of providing morphology and molecular information simultaneously. An ultrasonic transducer was applied for detecting PA signals and performing US imaging which determines the sensitivity and performance of a dual-modality PA/US system. In our study, a miniature single element 32-MHz lead magnesium niobate-lead titanate (PMN-PT) epoxy 1-3 composite based ultrasonic transducer was developed. A miniature endoscopic probe based on this transducer has been fabricated. Using the dual modality PA/US system with a PMN-PT/epoxy 1-3 composite based ultrasonic transducer, phantom and in vivo animal studies have been conducted to evaluate the performance. The preliminary results show enhanced bandwidths of the new ultrasonic transducer and improved signal-to-noise ratio of PA and US images of rat colorectal wall compared with PMN-PT and lead zirconate titanate (PZT) composite based ultrasonic transducers.
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