Journal
OPEN FORUM INFECTIOUS DISEASES
Volume 6, Issue 11, Pages -Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofz427
Keywords
prosthetic valve endocarditis; long-term chronic suppressive antibiotic therapy; serum bactericidal activity; dalbavancin
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Here we describe a case of a methicillin-resistant coagulase-negative staphylococci prosthetic valve endocarditis in a patient considered not eligible for valve replacement due to high perioperative mortality risk and who did not tolerate oral antibiotic treatment. Under these circumstances, intravenous long-term chronic suppressive antibiotic therapy with dalbavancin, scheduling the doses using the serum bactericidal activity titers, proved to be safe and effective.
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