4.6 Review

WNT Signaling in Disease

Journal

CELLS
Volume 8, Issue 8, Pages -

Publisher

MDPI
DOI: 10.3390/cells8080826

Keywords

WNT; cancer; metabolic syndrome; Alzheimer's disease

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Funding

  1. Ministry of Education of Singapore through Yale-NUS [IG17-LR006, IG18-LR001]

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Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments.

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