Journal
CHEMISTRYSELECT
Volume 4, Issue 34, Pages 10054-10059Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.201902419
Keywords
Aromatization; DFT; DMSO; Iodine; Marine-beta-carboline alkaloids
Categories
Funding
- UGC-BSR, UGC-New Delhi [F.4-3/2006(BSR)]
- EUPHRATES, an Erasmus Mundus Lot 13 project (Europe, India) [2013-2540/001-001]
- Council of Scientific & Industrial Research (CSIR), India [02(0357)/19/EMR-II]
- UGC
- University Grant Commission (UGC) Faculty Research Program, New Delhi, India
Ask authors/readers for more resources
A new protocol for the chemoselective aromatization of tetrahydro-beta-carboline-3-carboxylic acids to direct biomimetic one step synthesis of beta-carboline-3-carboxylic acids 2 A-L using catalytic amount of I-2 in DMSO/H+ produces very good yield. This method was also successfully extended for the aromatization of tetrahydro-beta-carboline-3-methyl esters 5 A-G as well as one-step synthesis of Marinacarbolines-D analog, respectively. Further, the mechanism and role of iodine-DMSO in aromatization has been studied by Density Functional Theory Calculation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
