4.5 Review

Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

Journal

FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING
Volume 14, Issue 3, Pages 365-377

Publisher

SPRINGER
DOI: 10.1007/s11705-019-1863-7

Keywords

carbohydrate; leptin; glyco-functionalised QD; bioimaging; cancer diagnosis and treatment

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Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.

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