Related references
Note: Only part of the references are listed.The Contribution of Genetic Variants of the Peroxisome Proliferator-Activated Receptor-Alpha Gene to High-Altitude Hypoxia Adaptation in Sherpa Highlanders
Fumiya Kinota et al.
HIGH ALTITUDE MEDICINE & BIOLOGY (2023)
The independent effects of hypovolaemia and pulmonary vasoconstriction on ventricular function and exercise capacity during acclimatisation to 3800 m
Mike Stembridge et al.
JOURNAL OF PHYSIOLOGY-LONDON (2019)
Supraspinal Fatigue and Neural-evoked Responses in Lowlanders and Sherpa at 5050 m
Luca Ruggiero et al.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2019)
Baroreflex control of sympathetic vasomotor activity and resting arterial pressure at high altitude: insight from Lowlanders and Sherpa
Lydia L. Simpson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2019)
Recruitment of non-perfused sublingual capillaries increases microcirculatory oxygen extraction capacity throughout ascent to 7126 m
Matthias Peter Hilty et al.
JOURNAL OF PHYSIOLOGY-LONDON (2019)
Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics?
Andrew F. Cumpstey et al.
REDOX BIOLOGY (2019)
Physiological Responses in Humans Acutely Exposed to High Altitude (3480 m): Minute Ventilation and Oxygenation Are Predictive for the Development of Acute Mountain Sickness
Martin Burtscher et al.
HIGH ALTITUDE MEDICINE & BIOLOGY (2019)
Sustained sympathetic activity in altitude acclimatizing lowlanders and high-altitude natives
C. Lundby et al.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS (2018)
Extreme pregnancy: maternal physical activity at Everest Base Camp
Margie H. Davenport et al.
JOURNAL OF APPLIED PHYSIOLOGY (2018)
Chemoreflex mediated arrhythmia during apnea at 5,050 m in low- but not high-altitude natives
Stephen A. Busch et al.
JOURNAL OF APPLIED PHYSIOLOGY (2018)
Demographic History and Genetic Adaptation in the Himalayan Region Inferred from Genome-Wide SNP Genotypes of 49 Populations
Elena Arciero et al.
MOLECULAR BIOLOGY AND EVOLUTION (2018)
Blunted nitric oxide regulation in Tibetans under high-altitude hypoxia
Yaoxi He et al.
NATIONAL SCIENCE REVIEW (2018)
UBC-Nepal expedition: upper and lower limb conduit artery shear stress and flow-mediated dilation on ascent to 5,050 m in lowlanders and Sherpa
Joshua C. Tremblay et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)
Sustained vasomotor control of skin microcirculation in Sherpas versus altitude-naive lowlanders: Experimental evidence from Xtreme Everest 2
Thomas Davies et al.
EXPERIMENTAL PHYSIOLOGY (2018)
UBC-Nepal expedition: peripheral fatigue recovers faster in Sherpa than lowlanders at high altitude
Luca Ruggiero et al.
JOURNAL OF PHYSIOLOGY-LONDON (2018)
Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal
Choongwon Jeong et al.
PLOS GENETICS (2018)
Evidence of Polygenic Adaptation to High Altitude from Tibetan and Sherpa Genomes
Guido A. Gnecchi-Ruscone et al.
GENOME BIOLOGY AND EVOLUTION (2018)
UBC-Nepal Expedition: An experimental overview of the 2016 University of British Columbia Scientific Expedition to Nepal Himalaya
Christopher K. Willie et al.
PLOS ONE (2018)
The earliest human occupation of the high-altitude Tibetan Plateau 40 thousand to 30 thousand years ago
X. L. Zhang et al.
SCIENCE (2018)
Neurovascular Coupling Remains Intact During Incremental Ascent to High Altitude (4240 m) in Acclimatized Healthy Volunteers
Jack K. Leacy et al.
FRONTIERS IN PHYSIOLOGY (2018)
Submaximal exercise testing at low altitude for prediction of exercise tolerance at high altitude
Martin Burtscher et al.
JOURNAL OF TRAVEL MEDICINE (2018)
The effect of α1-adrenergic blockade on post-exercise brachial artery flow-mediated dilatation at sea level and high altitude
Michael M. Tymko et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Sherpas share genetic variations with Tibetans for high-altitude adaptation
Sushil Bhandari et al.
MOLECULAR GENETICS & GENOMIC MEDICINE (2017)
Changes in acute pulmonary vascular responsiveness to hypoxia during a progressive ascent to high altitude (5300m)
Andrew M. Luks et al.
EXPERIMENTAL PHYSIOLOGY (2017)
UBC-Nepal Expedition: acute alterations in sympathetic nervous activity do not influence brachial artery endothelial function at sea level and high altitude
Michael M. Tymko et al.
JOURNAL OF APPLIED PHYSIOLOGY (2017)
Sublingual microcirculatory blood flow and vessel density in Sherpas at high altitude
Edward Gilbert-Kawai et al.
JOURNAL OF APPLIED PHYSIOLOGY (2017)
Measuring high-altitude adaptation
Lorna G. Moore
JOURNAL OF APPLIED PHYSIOLOGY (2017)
Oxygen saturation increases over the course of the night in mountaineers at high altitude (3050-6354 m)
Markus Tannheimer et al.
JOURNAL OF TRAVEL MEDICINE (2017)
Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia
Yi Peng et al.
MOLECULAR BIOLOGY AND EVOLUTION (2017)
Effects of dietary nitrate on respiratory physiology at high altitude - Results from the Xtreme Alps study
Andrew F. Cumpstey et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2017)
Metabolic basis to Sherpa altitude adaptation
James A. Horscroft et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
The genomic landscape of Nepalese Tibeto-Burmans reveals new insights into the recent peopling of Southern Himalayas
Guido A. Gnecchi-Ruscone et al.
SCIENTIFIC REPORTS (2017)
Evolutionary history of Tibetans inferred from whole-genome sequencing
Hao Hu et al.
PLOS GENETICS (2017)
Oscillatory shear stress, flow-mediated dilatation, and circulating microparticles at sea level and high altitude
Joshua C. Tremblay et al.
ATHEROSCLEROSIS (2017)
Antioxidant defense and oxidative damage vary widely among high-altitude residents
Allison J. Janocha et al.
AMERICAN JOURNAL OF HUMAN BIOLOGY (2017)
Differentiated demographic histories and local adaptations between Sherpas and Tibetans
Chao Zhang et al.
GENOME BIOLOGY (2017)
Ethnically Tibetan women in Nepal with low hemoglobin concentration have better reproductive outcomes
Jang Ik Cho et al.
EVOLUTION MEDICINE AND PUBLIC HEALTH (2017)
Genetic structure in the Sherpa and neighboring Nepalese populations
Amy M. Cole et al.
BMC GENOMICS (2017)
Ancestral Origins and Genetic History of Tibetan Highlanders
Dongsheng Lu et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
The mechanics of head-supported load carriage by Nepalese porters
G. J. Bastien et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2016)
Genome-Wide Transcriptional Analysis Reveals the Protection against Hypoxia-Induced Oxidative Injury in the Intestine of Tibetans via the Inhibition of GRB2/EGFR/PTPN11 Pathways
Kang Li et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
PLACENTAL ORIGINS OF CHRONIC DISEASE
Graham J. Burton et al.
PHYSIOLOGICAL REVIEWS (2016)
Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc
Choongwon Jeong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
A 3.4-kb Copy-Number Deletion near EPAS1 Is Significantly Enriched in High-Altitude Tibetans but Absent from the Denisovan Sequence
Haiyi Lou et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
Suppression of erythropoiesis by dietary nitrate
Tom Ashmore et al.
FASEB JOURNAL (2015)
Peroxisome proliferator-activated receptors in the regulation of female reproductive functions
Iwona Bogacka et al.
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2015)
Altitude Adaptation: A Glimpse Through Various Lenses
Tatum S. Simonson
HIGH ALTITUDE MEDICINE & BIOLOGY (2015)
Low haemoglobin concentration in Tibetan males is associated with greater high-altitude exercise capacity
T. S. Simonson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2015)
Genetic evidence of a recent Tibetan ancestry to Sherpas in the Himalayan region
Sushil Bhandari et al.
SCIENTIFIC REPORTS (2015)
Short-term adaptation and chronic cardiac remodelling to high altitude in lowlander natives and Himalayan Sherpa
Mike Stembridge et al.
EXPERIMENTAL PHYSIOLOGY (2015)
Changes in muscle proteomics in the course of the Caudwell Research Expedition to Mt. Everest
Denny Z. H. Levett et al.
PROTEOMICS (2015)
Cardiovascular function in healthy Himalayan high-altitude dwellers
R. M. Bruno et al.
ATHEROSCLEROSIS (2014)
Population history and genomic signatures for high-altitude adaptation in Tibetan pigs
Huashui Ai et al.
BMC GENOMICS (2014)
Pulmonary circulation and gas exchange at exercise in Sherpas at high altitude
Vitalie Faoro et al.
JOURNAL OF APPLIED PHYSIOLOGY (2014)
Ventricular structure, function, and mechanics at high altitude: chronic remodeling in Sherpa vs. short-term lowlander adaptation
Mike Stembridge et al.
JOURNAL OF APPLIED PHYSIOLOGY (2014)
Defective Tibetan PHD2 Binding to p23 Links High Altitude Adaption to Altered Oxygen Sensing
Daisheng Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Conduit artery structure and function in lowlanders and native highlanders: relationships with oxidative stress and role of sympathoexcitation
Nia C. S. Lewis et al.
JOURNAL OF PHYSIOLOGY-LONDON (2014)
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA
Emilia Huerta-Sanchez et al.
NATURE (2014)
A genetic mechanism for Tibetan high-altitude adaptation
Felipe R. Lorenzo et al.
NATURE GENETICS (2014)
King of the Mountains: Tibetan and Sherpa Physiological Adaptations for Life at High Altitude
Edward T. Gilbert-Kawai et al.
PHYSIOLOGY (2014)
Admixture facilitates genetic adaptations to high altitude in Tibet
Choongwon Jeong et al.
NATURE COMMUNICATIONS (2014)
Erythrocytosis and Pulmonary Hypertension in a Mouse Model of Human HIF2A Gain of Function Mutation
Qiulin Tan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
Tammie Bishop et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
mtDNA Lineage Expansions in Sherpa Population Suggest Adaptive Evolution in Tibetan Highlands
Longli Kang et al.
MOLECULAR BIOLOGY AND EVOLUTION (2013)
Genetic Evidence of Paleolithic Colonization and Neolithic Expansion of Modern Humans on the Tibetan Plateau
Xuebin Qi et al.
MOLECULAR BIOLOGY AND EVOLUTION (2013)
Identification of a Tibetan-Specific Mutation in the Hypoxic Gene EGLN1 and Its Contribution to High-Altitude Adaptation
Kun Xiang et al.
MOLECULAR BIOLOGY AND EVOLUTION (2013)
Recent human adaptation: genomic approaches, interpretation and insights
Laura B. Scheinfeldt et al.
NATURE REVIEWS GENETICS (2013)
Genomic Analysis of Natural Selection and Phenotypic Variation in High-Altitude Mongolians
Jinchuan Xing et al.
PLOS GENETICS (2013)
Nitric oxide in adaptation to altitude
Cynthia M. Beall et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
High altitude adaptation in Daghestani populations from the Caucasus
Luca Pagani et al.
HUMAN GENETICS (2012)
Genetic Variants in EPAS1 Contribute to Adaptation to High-Altitude Hypoxia in Sherpas
Masayuki Hanaoka et al.
PLOS ONE (2012)
Genetic adaptation to high altitude in the Ethiopian highlands
Laura B. Scheinfeldt et al.
GENOME BIOLOGY (2012)
Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp
Cameron J. Holloway et al.
FASEB JOURNAL (2011)
Peopling the Tibetan Plateau: Insights from Archaeology
Mark Aldenderfer
HIGH ALTITUDE MEDICINE & BIOLOGY (2011)
Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia-an ultrasound and MRI study
Mark H. Wilson et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)
Angiopoietin-1 is essential in mouse vasculature during development and in response to injury
Marie Jeansson et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
A Genome-Wide Search for Signals of High-Altitude Adaptation in Tibetans
Shuhua Xu et al.
MOLECULAR BIOLOGY AND EVOLUTION (2011)
Genetic Variations in Tibetan Populations and High-Altitude Adaptation at the Himalayas
Yi Peng et al.
MOLECULAR BIOLOGY AND EVOLUTION (2011)
On the Origin of Tibetans and Their Genetic Basis in Adapting High-Altitude Environments
Binbin Wang et al.
PLOS ONE (2011)
Humans at high altitude: Hypoxia and fetal growth
Lorna G. Moore et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2011)
Beyond oxygen: complex regulation and activity of hypoxia inducible factors in pregnancy
K. G. Pringle et al.
HUMAN REPRODUCTION UPDATE (2010)
High-altitude pulmonary hypertension is associated with a free radical-mediated reduction in pulmonary nitric oxide bioavailability
Damian M. Bailey et al.
JOURNAL OF PHYSIOLOGY-LONDON (2010)
The Effect of High-Altitude on Human Skeletal Muscle Energetics: 31P-MRS Results from the Caudwell Xtreme Everest Expedition
Lindsay M. Edwards et al.
PLOS ONE (2010)
Natural selection on EPAS1 (HIF2α) associated with low hemoglobin concentration in Tibetan highlanders
Cynthia M. Beall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Genetic Evidence for High-Altitude Adaptation in Tibet
Tatum S. Simonson et al.
SCIENCE (2010)
Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
Xin Yi et al.
SCIENCE (2010)
Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data
Abigail Bigham et al.
PLOS GENETICS (2010)
Angiogenic/lymphangiogenic factors and adaptation to extreme altitudes during an expedition to Mount Everest
M. Patitucci et al.
ACTA PHYSIOLOGICA (2009)
Evolutionary Adaptation to High Altitude: A View From In Utero
Colleen Glyde Julian et al.
AMERICAN JOURNAL OF HUMAN BIOLOGY (2009)
The Role of Hypoxia in Development of the Mammalian Embryo
Sally L. Dunwoodie
DEVELOPMENTAL CELL (2009)
Abnormal blood flow in the sublingual microcirculation at high altitude
Daniel S. Martin et al.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2009)
Arterial Blood Gases and Oxygen Content in Climbers on Mount Everest
Michael P. W. Grocott et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Metabolic adaptation of skeletal muscle to high altitude hypoxia: how new technologies could resolve the controversies
Andrew J. Murray
GENOME MEDICINE (2009)
Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins
Kotaro Takeda et al.
BLOOD (2008)
A gain-of-function mutation in the HIF2A gene in familial erythrocytosis
Melanie J. Percy et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Adaptation with the to high altitude in sherpas: Association insertion/deletion polymorphism in the angiotensin-converting enzyme gene
Yunden Droma et al.
WILDERNESS & ENVIRONMENTAL MEDICINE (2008)
PPAR Signaling in Placental Development and Function
Yaacov Barak et al.
PPAR RESEARCH (2008)
Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans
S. C. Erzurum et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Essential role for prolyl hydroxylase domain protein 2 in oxygen Homeostasis of the adult vascular system
Kotaro Takeda et al.
CIRCULATION (2007)
Role of the altitude level on cerebral autoregulation in residents at high altitude
Gerard F. A. Jansen et al.
JOURNAL OF APPLIED PHYSIOLOGY (2007)
A comparative analysis of arterial oxygen saturation among Tibetans and han born and raised at high altitude
Charles A. Weitz et al.
HIGH ALTITUDE MEDICINE & BIOLOGY (2007)
Acute postnatal ablation of Hif-2α results in anemia
Michaela Gruber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Placental but not heart defects are associated with elevated hypoxia-inducible factor α levels in mice lacking prolyl hydroxylase domain protein 2
Kotaro Takeda et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
High altitude adaptation in Tibetans
Tianyi Wu et al.
HIGH ALTITUDE MEDICINE & BIOLOGY (2006)
Energetics of load carrying in Nepalese porters
GJ Bastien et al.
SCIENCE (2005)
Consensus statement on chronic and subacute high altitude diseases
F León-Velarde et al.
HIGH ALTITUDE MEDICINE & BIOLOGY (2005)
Effect of load and speed on the energetic cost of human walking
GJ Bastien et al.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2005)
Second generation Tibetan lowlanders acclimatize to high altitude more quickly than Caucasians
C Marconi et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Higher offspring survival among Tibetan women with high oxygen saturation genotypes residing at 4,000 m
CM Beall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
New aspects of altitude adaptation in Tibetans: a proteomic approach
C Gelfi et al.
FASEB JOURNAL (2004)
Genetic variation in hypoxia-inducible factor 1α and its possible association with high altitude adaptation in Sherpas
K Suzuki et al.
MEDICAL HYPOTHESES (2003)
Peroxisome proliferator-activated receptors (PPARS): regulators of gene expression in heart and skeletal muscle
AJ Gilde et al.
ACTA PHYSIOLOGICA SCANDINAVICA (2003)
Fetal growth restriction and maternal oxygen transport during high altitude pregnancy
LG Moore
HIGH ALTITUDE MEDICINE & BIOLOGY (2003)
Human performance: A role for the ACE genotype?
A Jones et al.
EXERCISE AND SPORT SCIENCES REVIEWS (2002)
Spirometry values in Himalayan high altitude residents (Sherpas)
AP Havryk et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2002)
Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor α expression during hypoxia
S Narravula et al.
JOURNAL OF IMMUNOLOGY (2001)
Hypoxia decreases exhaled nitric oxide in mountaineers susceptible to high-altitude pulmonary edema
T Busch et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2001)
Peripheral arterial vascular function at altitude: sea-level natives versus Himalayan high-altitude natives
A Schneider et al.
JOURNAL OF HYPERTENSION (2001)
Cerebral autoregulation in subjects adapted and not adapted to high altitude
GFA Jansen et al.
STROKE (2000)
Share Paper
