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Jianhui Xie et al.
JOURNAL OF IMMUNOLOGY (2010)
Exogenous protein Hsp70/Hsc70 can penetrate into brain structures and attenuate the severity of chemically-induced seizures
Irina V. Ekimova et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Nanodisc-Incorporated Hemagglutinin Provides Protective Immunity against Influenza Virus Infection
Palash Bhattacharya et al.
JOURNAL OF VIROLOGY (2010)
The Heat Shock Response: Life on the Verge of Death
Klaus Richter et al.
MOLECULAR CELL (2010)
Microglia in the aging brain: relevance to neurodegeneration
Xiao-Guang Luo et al.
MOLECULAR NEURODEGENERATION (2010)
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
Cameron R. Stewart et al.
NATURE IMMUNOLOGY (2010)
`The HSP70 chaperone machinery: J proteins as drivers of functional specificity
Harm H. Kampinga et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Age-related changes in HSP25 expression in basal ganglia and cortex of F344/BN rats
Anisha A. Gupte et al.
NEUROSCIENCE LETTERS (2010)
HSF1-Controlled and Age-Associated Chaperone Capacity in Neurons and Muscle Cells of C. elegans
Andreas Kern et al.
PLOS ONE (2010)
αB Crystallin Is Apically Secreted within Exosomes by Polarized Human Retinal Pigment Epithelium and Provides Neuroprotection to Adjacent Cells
Parameswaran G. Sreekumar et al.
PLOS ONE (2010)
Heat Shock Protein 27 Protects Against Atherogenesis via an Estrogen-Dependent Mechanism Role of Selective Estrogen Receptor Beta Modulation
Katey Rayner et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib
Johann Kern et al.
BLOOD (2009)
Regulation of HSP27 on NF-κB pathway activation may be involved in metastatic hepatocellular carcinoma cells apoptosis
Kun Guo et al.
BMC CANCER (2009)
Guidelines for the nomenclature of the human heat shock proteins
Harm H. Kampinga et al.
CELL STRESS & CHAPERONES (2009)
The Shock of Aging: Molecular Chaperones and the Heat Shock Response in Longevity and Aging - A Mini-Review
Stuart K. Calderwood et al.
GERONTOLOGY (2009)
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
Vanessa Brochard et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor
L. Stefano et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2009)
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
Arthur Liesz et al.
NATURE MEDICINE (2009)
alpha-Crystallin Downregulates the Expression of TNF-alpha and iNOS by Activated Rat Retinal Microglia in vitro and in vivo
Nan Wu et al.
OPHTHALMIC RESEARCH (2009)
Serum Heat Shock Protein 27 Is Increased in Chronic Pancreatitis and Pancreatic Carcinoma
Wei-Chih Liao et al.
PANCREAS (2009)
Role of Interleukin-1β in Early Brain Injury After Subarachnoid Hemorrhage in Mice
Takumi Sozen et al.
STROKE (2009)
Membrane-associated stress proteins:: More than simply chaperones
Ibolya Horvath et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)
Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A
Katey Rayner et al.
CIRCULATION RESEARCH (2008)
Heat shock proteins: essential proteins for apoptosis regulation
D. Lanneau et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages
Virginia L. Vega et al.
JOURNAL OF IMMUNOLOGY (2008)
A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS
Seija Lehnardt et al.
JOURNAL OF NEUROSCIENCE (2008)
Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra
Vikas Kaushal et al.
JOURNAL OF NEUROSCIENCE (2008)
Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice
Suzanne E. Hickman et al.
JOURNAL OF NEUROSCIENCE (2008)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
Synuclein activates microglia in a model of Parkinson's disease
Xiaomin Su et al.
NEUROBIOLOGY OF AGING (2008)
MMP-9-Positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke
Anna Rosell et al.
STROKE (2008)
Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke
Zhen Zheng et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2008)
Hsp90 - From signal transduction to cell transformation
Mark A. Brown et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor
Sachiye Inouye et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Regulation of heat shock protein 70 release in astrocytes: Role of signaling kinases
Anna R. Taylor et al.
DEVELOPMENTAL NEUROBIOLOGY (2007)
Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease
Heiko Braak et al.
ACTA NEUROPATHOLOGICA (2007)
Deletion of tumor necrosis factor death receptor inhibits amyloid β generation and prevents learning and memory deficits in Alzheimer's mice
Ping He et al.
JOURNAL OF CELL BIOLOGY (2007)
Diverse regulatory activity of human heat shock proteins 60 and 70 on endotoxin-induced inflammation
Joerg M. Bangen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Polymorphonuclear leukocytes promote neurotoxicity through release of matrix metalloproteinases, reactive oxygen species, and TNF-α
Hal X. Nguyen et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Extracellular heat shock proteins in cell signaling
Stuart K. Calderwood et al.
FEBS LETTERS (2007)
Protective and therapeutic role for αB-crystallin in autoimmune demyelination
Shalina S. Ousman et al.
NATURE (2007)
HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway
Sanjiv Gupta et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Absence of the chemokine receptor CCR2 protects against cerebral Ischemia/reperfusion injury in mice
Olivier B. Dimitrijevic et al.
STROKE (2007)
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
Joseph El Khoury et al.
NATURE MEDICINE (2007)
Protein profiling of microdissected pancreas carcinoma and identification of HSP27 as a potential serum marker
Christian Melle et al.
CLINICAL CHEMISTRY (2007)
Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4+ T cells and dendritic cells
Jeffrey Pido-Lopez et al.
JOURNAL OF IMMUNOLOGY (2007)
Role of scavenger receptors in the binding and internalization of heat shock protein 70
Jimmy R. Theriault et al.
JOURNAL OF IMMUNOLOGY (2006)
Heat induced release of Hsp70 from prostate carcinoma cells involves both active secretion and passive release from necrotic cells
Salamatu S. Mambula et al.
INTERNATIONAL JOURNAL OF HYPERTHERMIA (2006)
Suppression of NF-κB activation by Entamoeba histolytica in intestinal epithelial cells is mediated by heat shock Protein 27
Srinivas J. Kammanadiminti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Small heat shock proteins inhibit amyloid-β protein aggregation and cerebrovascular amyloid-β protein toxicity
Micha M. M. Wilhelmus et al.
BRAIN RESEARCH (2006)
Geranylgeranylacetone, a noninvasive heat shock protein inducer, induces protein kinase C and leads to neuroprotection against cerebral infarction in rats
S Uchida et al.
NEUROSCIENCE LETTERS (2006)
Microglia potentiate damage to blood-brain barrier constituents - Improvement by minocycline in vivo and in vitro
MA Yenari et al.
STROKE (2006)
Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains
MMM Wilhelmus et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2006)
Molecular chaperone α-crystallin prevents detrimental effects of neuroinflammation
JG Masilamoni et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
AR Simard et al.
NEURON (2006)
Exogenous heat shock protein 70 binds macrophage lipid raft microdomain and stimulates phagocytosis, processing, and MHC-II presentation of antigens
RB Wang et al.
BLOOD (2006)
Heat-shock protein 27: A potential biomarker for hepatocellular carcinoma identified by serum proteome analysis
JT Feng et al.
PROTEOMICS (2005)
Enhanced expression of heat shock proteins in gradually dying cells and their release from necrotically dead cells
K Saito et al.
EXPERIMENTAL CELL RESEARCH (2005)
TLR signaling tailors innate immune responses in human microglia and astrocytes
CS Jack et al.
JOURNAL OF IMMUNOLOGY (2005)
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
M Kitazawa et al.
JOURNAL OF NEUROSCIENCE (2005)
Induction of heat shock proteins in B-cell exosomes
A Clayton et al.
JOURNAL OF CELL SCIENCE (2005)
Effect of interleukin-1 on traumatic brain injury - Induced damage to hippocampal neurons
KT Lu et al.
JOURNAL OF NEUROTRAUMA (2005)
Tumor necrosis factor-α neutralization reduced cerebral edema through inhibition of matrix metalloproteinase production after transient focal cerebral ischemia
N Hosomi et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2005)
Not all J domains are created equal: Implications for the specificity of Hsp40-Hsp70 interactions
F Hennessy et al.
PROTEIN SCIENCE (2005)
Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells
R Gastpar et al.
CANCER RESEARCH (2005)
Ineffective phagocytosis of amyloid-β by macrophages of Alzheimer's disease patients
M Fiala et al.
JOURNAL OF ALZHEIMERS DISEASE (2005)
ATP mediates rapid microglial response to local brain injury in vivo
D Davalos et al.
NATURE NEUROSCIENCE (2005)
Heat-shock proteins induce T-cell regulation of chronic inflammation
W van Eden et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Hsp70 chaperones: Cellular functions and molecular mechanism
MP Mayer et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2005)
Celastrol Blocks Neuronal Cell Death and Extends Life in Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
Mahmoud Kiaei et al.
NEURODEGENERATIVE DISEASES (2005)
Heat shock proteins as endogenous adjuvants in sterile and septic inflammation
FJ Quintana et al.
JOURNAL OF IMMUNOLOGY (2005)
Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival
H Shimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
D Kieran et al.
NATURE MEDICINE (2004)
HSP27 but not HSP70 has a potent protective effect against α-synuclein-induced cell death in mammalian neuronal cells
A Zourlidou et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Administration of Hsp70 in vivo inhibits motor and sensory neuron degeneration
JL Tidwell et al.
CELL STRESS & CHAPERONES (2004)
Celastrols as inducers of the heat shock response and cytoprotection
SD Westerheide et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Paeoniflorin, a novel heat shock protein-inducing compound
D Yan et al.
CELL STRESS & CHAPERONES (2004)
Hsp70 release from peripheral blood mononuclear cells
C Hunter-Lavin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Herbimycin A induces sympathetic neuron survival and protects against hypoxia
MC Cabral-da-Silva et al.
NEUROREPORT (2003)
The effect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fibers of the rat following peripheral nerve injury
B Kalmar et al.
EXPERIMENTAL NEUROLOGY (2003)
TNFα mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of the HSF1/hsp70 stress response
G Schett et al.
CELL DEATH AND DIFFERENTIATION (2003)
Intrathecal inflammation precedes development of Alzheimer's disease
E Tarkowski et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2003)
Interferon γ stimulates β-secretase expression and sAPPβ production in astrocytes
HS Hong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
BGP-15, a hydroximic acid derivative, protects against cisplatin or taxol-induced peripheral neuropathy in rats
G Bárdos et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2003)
Heat shock protein-90-induced microglial clearance of exogenous amyloid-β1-42 in rat hippocampus in vivo
K Takata et al.
NEUROSCIENCE LETTERS (2003)
Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release
AH Broquet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Interleukin-1 and neuronal injury: mechanisms, modification, and therapeutic potential
N Rothwell
BRAIN BEHAVIOR AND IMMUNITY (2003)
On the role of Hsp27 in regulating apoptosis
CG Concannon et al.
APOPTOSIS (2003)
CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes
T Becker et al.
JOURNAL OF CELL BIOLOGY (2002)
Upregulation of heat shock proteins rescues motoneurones from axotomy-induced cell death in neonatal rats
B Kalmar et al.
EXPERIMENTAL NEUROLOGY (2002)
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin
A Wyttenbach et al.
HUMAN MOLECULAR GENETICS (2002)
A high affinity HSF-1 binding site in the 5′-untranslated region of the murine tumor necrosis factor-α gene is a transcriptional repressor
IS Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Hyperlipidemia induced by high cholesterol diet inhibits heat shock response in rat hearts
T Csont et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Microglial activation and amyloid-β clearance induced by exogenous heat-shock proteins
J Kakimura et al.
FASEB JOURNAL (2002)
Thermal preconditioning and heat-shock protein 72 preserve synaptic transmission during thermal stress
JD Kelty et al.
JOURNAL OF NEUROSCIENCE (2002)
In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance
I Guzhova et al.
BRAIN RESEARCH (2001)
Evolution of cerebral tumor necrosis factor-α production during human ischemic stroke
T Sairanen et al.
STROKE (2001)
CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
S Basu et al.
IMMUNITY (2001)
IL-4, IL-10 and IL-13 modulate Aβ(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line
AM Szczepanik et al.
JOURNAL OF NEUROIMMUNOLOGY (2001)
Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway
S Basu et al.
INTERNATIONAL IMMUNOLOGY (2000)
Multiple molecular penumbras after focal cerebral ischemia
FR Sharp et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2000)
Age-related alterations in the activation of heat shock transcription factor 1 in rat hepatocytes
AR Heydari et al.
EXPERIMENTAL CELL RESEARCH (2000)
HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
A Asea et al.
NATURE MEDICINE (2000)
Molecular chaperones and the aging process
C Soti et al.
BIOGERONTOLOGY (2000)
Brain tissue responses to ischemia
JM Lee et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)