Related references
Note: Only part of the references are listed.The role of systems biology approaches in determining molecular signatures for the development of more effective vaccines
Abdulmohammad Pezeshki et al.
EXPERT REVIEW OF VACCINES (2019)
Effect of latent cytomegalovirus infection on the antibody response to influenza vaccination: a systematic review and meta-analysis
S. P. H. van den Berg et al.
MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2019)
Body composition changes in diabetes and aging
Mohammed E. Al-Sofiani et al.
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2019)
Severe Morbidity and Mortality Associated With Respiratory Syncytial Virus Versus Influenza Infection in Hospitalized Older Adults
Bradley Ackerson et al.
CLINICAL INFECTIOUS DISEASES (2019)
Will Systems Biology Deliver Its Promise and Contribute to the Development of New or Improved Vaccines? From Data to Understanding through Systems Biology
Thomas Hagan et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
Shingrix: The New Adjuvanted Recombinant Herpes Zoster Vaccine
Stephanie F. James et al.
ANNALS OF PHARMACOTHERAPY (2018)
Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains
Chia-Hsin Ju et al.
CLINICAL IMMUNOLOGY (2018)
Signal transduction changes in CD4+ and CD8+ T cell subpopulations with aging
Aurelie Le Page et al.
EXPERIMENTAL GERONTOLOGY (2018)
Senescent B cells in aging and age-related diseases: Their role in the regulation of antibody responses
Daniela Frasca
EXPERIMENTAL GERONTOLOGY (2018)
Lymphoid tissue fibrosis is associated with impaired vaccine responses
Cissy Kityo et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Herpes Zoster Vaccines
Anthony L. Cunningham et al.
JOURNAL OF INFECTIOUS DISEASES (2018)
T-Cell Responses in Adults During Natural Respiratory Syncytial Virus Infection
D. Roumanes et al.
JOURNAL OF INFECTIOUS DISEASES (2018)
Immune Responses to a Recombinant Glycoprotein E Herpes Zoster Vaccine in Adults Aged 50 Years or Older
Anthony L. Cunningham et al.
JOURNAL OF INFECTIOUS DISEASES (2018)
Respiratory Syncytial Virus and Associations With Cardiovascular Disease in Adults
Kelsey S. Ivey et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)
Breadth and Functionality of Varicella-Zoster Virus Glycoprotein-Specific Antibodies Identified after Zostavax Vaccination in Humans
Nicole L. Sullivan et al.
JOURNAL OF VIROLOGY (2018)
Correlates of adjuvanticity: A review on adjuvants in licensed vaccines
Giuseppe Del Giudice et al.
SEMINARS IN IMMUNOLOGY (2018)
Influenza vaccine effectiveness in older adults compared with younger adults over five seasons
Kate Russell et al.
VACCINE (2018)
Transcriptomic signatures of cellular and humoral immune responses in older adults after seasonal influenza vaccination identified by data-driven clustering
Emily A. Voigt et al.
SCIENTIFIC REPORTS (2018)
Age-related differences in humoral and cellular immune responses after primary immunisation: indications for stratified vaccination schedules
Angelika Wagner et al.
SCIENTIFIC REPORTS (2018)
Age-Related Decline in Primary CD8+ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8+ T Cells
Kylie M. Quinn et al.
CELL REPORTS (2018)
Persistence of immune response to an adjuvanted varicella-zoster virus subunit vaccine for up to year nine in older adults
Tino F. Schwarz et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2018)
Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding
Sara D'Angelo et al.
FRONTIERS IN IMMUNOLOGY (2018)
Negative Effect of Age, but Not of Latent Cytomegalovirus Infection on the Antibody Response to a Novel Influenza Vaccine Strain in Healthy Adults
Sara P. H. van den Berg et al.
FRONTIERS IN IMMUNOLOGY (2018)
Single Cell RNA Sequencing of Rare immune Cell Populations
Akira Nguyen et al.
FRONTIERS IN IMMUNOLOGY (2018)
Th1 memory differentiates recombinant from live herpes zoster vaccines
Myron J. Levin et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Comparative Analysis of B-Cell Receptor Repertoires Induced by Live Yellow Fever Vaccine in Young and Middle-Age Donors
Alexey N. Davydov et al.
FRONTIERS IN IMMUNOLOGY (2018)
Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments
Jessica A. Belser et al.
EMERGING INFECTIOUS DISEASES (2018)
The twilight of immunity: emerging concepts in aging of the immune system
Janko Nikolich-Zugich
NATURE IMMUNOLOGY (2018)
The human viral challenge model: accelerating the evaluation of respiratory antivirals, vaccines and novel diagnostics
Rob Lambkin-Williams et al.
RESPIRATORY RESEARCH (2018)
Adjuvant system AS01: helping to overcome the challenges of modern vaccines
Arnaud M. Didierlaurent et al.
EXPERT REVIEW OF VACCINES (2017)
Effectiveness of influenza vaccines in preventing severe influenza illness among adults: A systematic review and meta-analysis of test-negative design case-control studies
Marc Rondy et al.
JOURNAL OF INFECTION (2017)
An Adjuvanted, Postfusion F Protein-Based Vaccine Did Not Prevent Respiratory Syncytial Virus Illness in Older Adults
Judith Falloon et al.
JOURNAL OF INFECTIOUS DISEASES (2017)
Human T cell immunosenescence and inflammation in aging
Arsun Bektas et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2017)
Distinct aging profiles of CD8+T cells in blood versus gastrointestinal mucosal compartments
Jeffrey Dock et al.
PLOS ONE (2017)
Animal models of respiratory syncytial virus infection
Geraldine Taylor
VACCINE (2017)
Effectiveness of MF59-adjuvanted seasonal influenza vaccine in the elderly: A systematic review and meta-analysis
Alexander Domnich et al.
VACCINE (2017)
The importance of RSV F protein conformation in VLPs in stimulation of neutralizing antibody titers in mice previously infected with RSV
Lori M. Cullen et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2017)
Role of Dendritic Cells in inflammation and Loss of Tolerance in the elderly
Anshu Agrawal et al.
FRONTIERS IN IMMUNOLOGY (2017)
Functional and Homeostatic impact of Age-Related Changes in Lymph node Stroma
Heather L. Thompson et al.
FRONTIERS IN IMMUNOLOGY (2017)
Effectiveness of the 23-Valent Pneumococcal Polysaccharide Vaccine (PPV23) against Pneumococcal Disease in the Elderly: Systematic Review and Meta-Analysis
Gerhard Falkenhorst et al.
PLOS ONE (2017)
Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains
Ivette A. Nunez et al.
PLOS ONE (2017)
Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells
Rossella Cioncada et al.
PLOS ONE (2017)
Risk of mortality associated with respiratory syncytial virus and influenza infection in adults
Yong Shik Kwon et al.
BMC INFECTIOUS DISEASES (2017)
Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules
Joanne K. Gardner et al.
AGEING RESEARCH REVIEWS (2017)
Memory-phenotype CD4+ T cells spontaneously generated under steady-state conditions exert innate TH1-like effector function
Takeshi Kawabe et al.
SCIENCE IMMUNOLOGY (2017)
Immune System Dysfunction in the Elderly
Eduardo Fuentes et al.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2017)
Reduced naive CD8+ T-cell priming efficacy in elderly adults
Olivia Briceno et al.
AGING CELL (2016)
CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+study
Ioakim Spyridopoulos et al.
AGING CELL (2016)
The ageing human B cell repertoire: a failure of selection?
D. K. Dunn-Walters
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2016)
Fluzone® High-Dose Influenza Vaccine
Corwin A. Robertson et al.
EXPERT REVIEW OF VACCINES (2016)
Declining Effectiveness of Herpes Zoster Vaccine in Adults Aged ≥60 Years
Hung Fu Tseng et al.
JOURNAL OF INFECTIOUS DISEASES (2016)
Men and mice: Relating their ages
Sulagna Dutta et al.
LIFE SCIENCES (2016)
Efficacy of the Herpes Zoster Subunit Vaccine in Adults 70 Years of Age or Older
A. L. Cunningham et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination
Michael T. Zimmermann et al.
PLOS ONE (2016)
The effectiveness of pneumococcal polysaccharide vaccine 23 (PPV23) in the general population of 50 years of age and older: A systematic review and meta-analysis
Hannah Kraicer-Melamed et al.
VACCINE (2016)
Transcriptional signatures of influenza A/H1N1-specific IgG memory-like B cell response in older individuals
Iana H. Haralambieva et al.
VACCINE (2016)
Long-term immunogenicity and safety of an investigational herpes zoster subunit vaccine in older adults
Roman Chlibek et al.
VACCINE (2016)
Advances in RSV vaccine research and development - A global agenda
Deborah Higgins et al.
VACCINE (2016)
Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus
Jennifer L. Uhrlaub et al.
PLOS PATHOGENS (2016)
Mechanisms Underlying T Cell Immunosenescence: Aging and Cytomegalovirus Infection
Wenjuan Tu et al.
FRONTIERS IN MICROBIOLOGY (2016)
Changes in blood lymphocyte numbers with age in vivo and their association with the levels of cytokines/cytokine receptors
Yun Lin et al.
IMMUNITY & AGEING (2016)
Immunosenescence-Related Transcriptomic and Immunologic Changes in Older Individuals Following Influenza Vaccination
Richard B. Kennedy et al.
FRONTIERS IN IMMUNOLOGY (2016)
T-Cell immunity to influenza in Older Adults: A Pathophysiological Framework for Development of More effective vaccines
Janet E. McElhaney et al.
FRONTIERS IN IMMUNOLOGY (2016)
Age-related impairment of humoral response to influenza is associated with changes in antigen specific T follicular helper cell responses
Julie S. Lefebvre et al.
SCIENTIFIC REPORTS (2016)
The aged lymphoid tissue environment fails to support naive T cell homeostasis
Bryan R. Becklund et al.
SCIENTIFIC REPORTS (2016)
Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus
Maximillian S. Habibi et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors
Curtis J. Henry et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals
Daniela Frasca et al.
JOURNAL OF IMMUNOLOGY (2015)
A CD153+CD4+ T Follicular Cell Population with Cell-Senescence Features Plays a Crucial Role in Lupus Pathogenesis via Osteopontin Production
Suhail Tahir et al.
JOURNAL OF IMMUNOLOGY (2015)
Naive T Cell Maintenance and Function in Human Aging
Joerg J. Goronzy et al.
JOURNAL OF IMMUNOLOGY (2015)
Effect of Preexisting Serum and Mucosal Antibody on Experimental Respiratory Syncytial Virus (RSV) Challenge and Infection of Adults
Bindiya Bagga et al.
JOURNAL OF INFECTIOUS DISEASES (2015)
Immunosenescence: Implications for response to infection and vaccination in older people
Alejandra Pera et al.
MATURITAS (2015)
Control of adaptive immunity by the innate immune system
Akiko Iwasaki et al.
NATURE IMMUNOLOGY (2015)
Efficacy of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults
Himal Lal et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Polysaccharide Conjugate Vaccine against Pneumococcal Pneumonia in Adults
M. J. M. Bonten et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Systems integration of innate and adaptive immunity
Daniel E. Zak et al.
VACCINE (2015)
Pneumococcal disease prevention among adults: Strategies for the use of pneumococcal vaccines
Tamara Pilishvili et al.
VACCINE (2015)
Systems vaccinology: Enabling rational vaccine design with systems biological approaches
Thomas Hagan et al.
VACCINE (2015)
Age-Dependent Cell Trafficking Defects in Draining Lymph Nodes Impair Adaptive Immunity and Control of West Nile Virus Infection
Justin M. Richner et al.
PLOS PATHOGENS (2015)
Cytomegalovirus Infection and Memory T Cell Inflation
Jihye Kim et al.
Immune Network (2015)
Long-term Persistence of Zoster Vaccine Efficacy
Vicki A. Morrison et al.
CLINICAL INFECTIOUS DISEASES (2015)
Plasma cell numbers decrease in bone marrow of old patients
Theresa Pritz et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
IFNγ-TNFα-IL2-MIP1α-CD107a+PRF1+ CD8 pp65-Specific T-Cell Response Is Independently Associated With Time to Death in Elderly Humans
Sara Ferrando-Martinez et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2015)
Chronic CMV infection in older women: Longitudinal comparisons of CMV DNA in peripheral monocytes, anti-CMV IgG titers, serum IL-6 levels, and CMV pp65 (NLV)-specific CD8+ T-cell frequencies with twelve year follow-up
Huifen Li et al.
EXPERIMENTAL GERONTOLOGY (2014)
High TNF-α levels in resting B cells negatively correlate with their response
Daniela Frasca et al.
EXPERIMENTAL GERONTOLOGY (2014)
The personal touch: strategies toward personalized vaccines and predicting immune responses to them
Richard B. Kennedy et al.
EXPERT REVIEW OF VACCINES (2014)
CyTOF supports efficient detection of immune cell subsets from small samples
Yi Yao et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2014)
Two Separate Defects Affecting True Naive or Virtual Memory T Cell Precursors Combine To Reduce Naive T Cell Responses with Aging
Kristin R. Renkema et al.
JOURNAL OF IMMUNOLOGY (2014)
Age-Related Decrease in TCR Repertoire Diversity Measured with Deep and Normalized Sequence Profiling
Olga V. Britanova et al.
JOURNAL OF IMMUNOLOGY (2014)
Aging and Cytomegalovirus Infection Differentially and Jointly Affect Distinct Circulating T Cell Subsets in Humans
Anne M. Wertheimer et al.
JOURNAL OF IMMUNOLOGY (2014)
Aging of the T Cell Compartment in Mice and Humans: From No Naive Expectations to Foggy Memories
Janko Nikolich-Zugich
JOURNAL OF IMMUNOLOGY (2014)
Dendritic Cells from Aged Subjects Display Enhanced Inflammatory Responses to Chlamydophila pneumoniae
Sangeetha Prakash et al.
MEDIATORS OF INFLAMMATION (2014)
Vaccines, new opportunities for a new society
Rino Rappuoli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Immunosenescence and pneumococcal disease: an imbalance in host-pathogen interactions
Cassandra L. Krone et al.
LANCET RESPIRATORY MEDICINE (2014)
The Biology of Recent Thymic Emigrants
Pamela J. Fink
ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)
Adults 65 Years Old and Older Have Reduced Numbers of Functional Memory T Cells to Respiratory Syncytial Virus Fusion Protein
Anu Cherukuri et al.
CLINICAL AND VACCINE IMMUNOLOGY (2013)
High Morbidity and Mortality in Adults Hospitalized for Respiratory Syncytial Virus Infections
N. Lee et al.
CLINICAL INFECTIOUS DISEASES (2013)
Pathogenesis and Current Approaches to Control of Varicella-Zoster Virus Infections
Anne A. Gershon et al.
CLINICAL MICROBIOLOGY REVIEWS (2013)
A comparative review of aging and B cell function in mice and humans
Jean L. Scholz et al.
CURRENT OPINION IN IMMUNOLOGY (2013)
Age effects on mouse and human B cells
Bonnie B. Blomberg et al.
IMMUNOLOGIC RESEARCH (2013)
Cutting Edge: Central Memory CD8 T Cells in Aged Mice Are Virtual Memory Cells
Bo-Chin Chiu et al.
JOURNAL OF IMMUNOLOGY (2013)
Influenza Illness and Hospitalizations Averted by Influenza Vaccination in the United States, 2005-2011
Deliana Kostova et al.
PLOS ONE (2013)
Long-term Effectiveness of Varicella Vaccine: A 14-Year, Prospective Cohort Study
Roger Baxter et al.
PEDIATRICS (2013)
Lineage Structure of the Human Antibody Repertoire in Response to Influenza Vaccination
Ning Jiang et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination
Evelyna Derhovanessian et al.
VACCINE (2013)
The aging lung
Elizabeth Kovacs et al.
Clinical Interventions in Aging (2013)
When aging reaches CD4+T-cells: phenotypic and functional changes
Marco Antonio Moro-Garcia et al.
FRONTIERS IN IMMUNOLOGY (2013)
Vaccines for preventing pneumococcal infection in adults
Sarah Moberley et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2013)
Fluad®-MF59®-Adjuvanted Influenza Vaccine in Older Adults
Theodore F. Tsai
INFECTION AND CHEMOTHERAPY (2013)
Animal Models of Varicella Zoster Virus Infection
Kristen Haberthur et al.
PATHOGENS (2013)
Age-associated alterations in CD8a+dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium
Gang Li et al.
AGING CELL (2012)
Development and clinical evaluation of Prevnar 13, a 13-valent pneumocococcal CRM197 conjugate vaccine
William C. Gruber et al.
PHARMACEUTICAL SCIENCE TO IMPROVE THE HUMAN CONDITION: PRIX GALIEN 2011 (2012)
Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans
Ineke den Braber et al.
IMMUNITY (2012)
Aging Population and Future Burden of Pneumococcal Pneumonia in the United States
Peter C. Wroe et al.
JOURNAL OF INFECTIOUS DISEASES (2012)
Effect of Influenza on Functional Decline
Pedro L. Gozalo et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2012)
Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis
Michael T. Osterholm et al.
LANCET INFECTIOUS DISEASES (2012)
Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
Guangjin Li et al.
NATURE MEDICINE (2012)
Age Affects Quantity but Not Quality of Antibody Responses after Vaccination with an Inactivated Flavivirus Vaccine against Tick-Borne Encephalitis
Karin Stiasny et al.
PLOS ONE (2012)
The mechanism of action of MF59 - An innately attractive adjuvant formulation
D. T. O'Hagan et al.
VACCINE (2012)
Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with Aging
Luka Cicin-Sain et al.
PLOS PATHOGENS (2012)
AID Activity in B Cells Strongly Correlates with Polyclonal Antibody Affinity Maturation in-vivo Following Pandemic 2009-H1N1 Vaccination in Humans
Surender Khurana et al.
PLOS PATHOGENS (2012)
Age-related changes in human peripheral blood IGH repertoire following vaccination
Yu-Chang Bryan Wu et al.
FRONTIERS IN IMMUNOLOGY (2012)
Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity
Aishwarya Sridharan et al.
AGE (2011)
B cells and immunosenescence: A focus on IgG+IgD-CD27- (DN) B cells in aged humans
Matteo Bulati et al.
AGEING RESEARCH REVIEWS (2011)
The Potential Role for Protein-Conjugate Pneumococcal Vaccine in Adults: What Is the Supporting Evidence?
Daniel M. Musher et al.
CLINICAL INFECTIOUS DISEASES (2011)
Older Adults Have a Low Capacity To Opsonize Pneumococci Due to Low IgM Antibody Response to Pneumococcal Vaccinations
Saeyoung Park et al.
INFECTION AND IMMUNITY (2011)
Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies
Sanae Sasaki et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
A Combination of Flt3 Ligand cDNA and CpG Oligodeoxynucleotide as Nasal Adjuvant Elicits Protective Secretory-IgA Immunity to Streptococcus pneumoniae in Aged Mice
Yoshiko Fukuyama et al.
JOURNAL OF IMMUNOLOGY (2011)
Impaired Interferon Signaling in Dendritic Cells From Older Donors Infected In Vitro With West Nile Virus
Feng Qian et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells
Jonathan Sprent et al.
NATURE IMMUNOLOGY (2011)
Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor: pMHC interactions
Brian D. Rudd et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
Wendy W. Pang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Th17/Th1 biased immunity to the pneumococcal proteins PcsB, StkP and PsaA in adults of different age
Petra Schmid et al.
VACCINE (2011)
Aging reduces the functionality of anti-pneumococcal antibodies and the killing of Streptococcus pneumoniae by neutrophil phagocytosis
Birgit Simell et al.
VACCINE (2011)
The impact of herpes zoster and post-herpetic neuralgia on quality-of-life
Robert W. Johnson et al.
BMC MEDICINE (2010)
Determining the Optimal Pneumococcal Vaccination Strategy for Adults Is There a Role for the Pneumococcal Conjugate Vaccine?
Mark L. Metersky et al.
CHEST (2010)
Aging of the innate immune system
Albert C. Shaw et al.
CURRENT OPINION IN IMMUNOLOGY (2010)
T cells and follicular dendritic cells in germinal center B-cell formation and selection
Carola G. Vinuesa et al.
IMMUNOLOGICAL REVIEWS (2010)
Cell-Intrinsic Defects in the Proliferative Response of Antiviral Memory CD8 T Cells in Aged Mice upon Secondary Infection
Vilma Decman et al.
JOURNAL OF IMMUNOLOGY (2010)
Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response
Alexander Panda et al.
JOURNAL OF IMMUNOLOGY (2010)
Antibody and cell-mediated immunity to Streptococcus pneumoniae: implications for vaccine development
Richard Malley
JOURNAL OF MOLECULAR MEDICINE-JMM (2010)
Effect of a Zoster Vaccine on Herpes Zoster-Related Interference with Functional Status and Health-Related Quality-of-Life Measures in Older Adults
Kenneth E. Schmader et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2010)
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
Isabel Beerman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Age related changes in T cell mediated immune response and effector memory to Respiratory Syncytial Virus (RSV) in healthy subjects
Maria Grazia Cusi et al.
Immunity & Ageing (2010)
B-cell diversity decreases in old age and is correlated with poor health status
Kate L. Gibson et al.
AGING CELL (2009)
Alterations in dendritic cell function in aged mice: potential implications for immunotherapy design
Carine Paula et al.
BIOGERONTOLOGY (2009)
Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood
Yu Jing et al.
HUMAN IMMUNOLOGY (2009)
A double-negative (IgD-CD27-) B cell population is increased in the peripheral blood of elderly people
Giuseppina Colonna-Romano et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2009)
B-cell responses to vaccination at the extremes of age
Claire-Anne Siegrist et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Effects of ageing and gender on naturally acquired antibodies to pneumococcal capsular polysaccharides and virulence-associated proteins
Birgit Simell et al.
CLINICAL AND VACCINE IMMUNOLOGY (2008)
Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus
Eric J. Yager et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells
Daniela Frasca et al.
JOURNAL OF IMMUNOLOGY (2008)
Pneumonia in the Elderly: A Review of the Epidemiology, Pathogenesis, Microbiology, and Clinical Features
Carol P. Chong et al.
SOUTHERN MEDICAL JOURNAL (2008)
Pneumococcal vaccination in older adults induces antibodies with low opsonic capacity and reduced antibody potency
Jeremy G. Schenkein et al.
VACCINE (2008)
Interleukin-17A mediates acquired immunity to pneumococcal colonization
Ying-Jie Lu et al.
PLOS PATHOGENS (2008)
Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates
Luka Cicin-Sain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Rectification of age-associated deficiency in cytotoxic T cell response to influenza a virus by immunization with immune complexes
Biao Zheng et al.
JOURNAL OF IMMUNOLOGY (2007)
Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA
Daniela Frasca et al.
JOURNAL OF IMMUNOLOGY (2007)
Altered innate immune functioning of dendritic cells in elderly humans: A role of phosphoinositide 3-kinase-signaling pathway
Anshu Agrawal et al.
JOURNAL OF IMMUNOLOGY (2007)
Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes
Marc Bajenoff et al.
IMMUNITY (2006)
Antibody quality in old age
WA Howard et al.
REJUVENATION RESEARCH (2006)
Memory B cell subpopulations in the aged
G Colonna-Romano et al.
REJUVENATION RESEARCH (2006)
Antibody response to influenza vaccination in the elderly: A quantitative review
K Goodwin et al.
VACCINE (2006)
Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly
SR Hadrup et al.
JOURNAL OF IMMUNOLOGY (2006)
A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults
MN Oxman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Respiratory syncytial virus-specific CD8+ memory T cell responses in elderly persons
GJ de Bree et al.
JOURNAL OF INFECTIOUS DISEASES (2005)
Respiratory syncytial virus infection in elderly and high-risk adults
AR Falsey et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Respiratory syncytial virus infection in elderly adults
AR Falsey et al.
DRUGS & AGING (2005)
Age-related loss of naive T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes
L Lazuardi et al.
IMMUNOLOGY (2005)
Age-related impaired type 1 T cell responses to influenza: Reduced activation ex vivo, decreased expansion in CTL culture in vitro, and blunted response to influenza vaccination in vivo in the elderly
YP Deng et al.
JOURNAL OF IMMUNOLOGY (2004)
Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase
D Frasca et al.
JOURNAL OF IMMUNOLOGY (2004)
Humoral and mucosal immunity in protection from natural respiratory syncytial virus infection in adults
EE Walsh et al.
JOURNAL OF INFECTIOUS DISEASES (2004)
Age-associated change in the frequency of memory CD4+ T cells impairs long term CD4+ T cell responses to influenza vaccine
IS Kang et al.
JOURNAL OF IMMUNOLOGY (2004)
CD27 is acquired by primed B cells at the centroblast stage and promotes germinal center formation
YL Xiao et al.
JOURNAL OF IMMUNOLOGY (2004)
Altered regulation of FcγRII on aged follicular dendritic cells correlates with immunoreceptor tyrosine-based inhibition motif signaling in B cells and reduced germinal center formation
Y Aydar et al.
JOURNAL OF IMMUNOLOGY (2003)
Type 1 and type 2 cytokine imbalance in acute respiratory syncytial virus bronchiolitis
JP Legg et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2003)
Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old
OY Qin et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2003)
E-proteins directly regulate expression of activation-induced deaminase in mature B cells
CE Sayegh et al.
NATURE IMMUNOLOGY (2003)
In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells
Q Yu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Protective mucosal immunity in aging is associated with functional CD4+ T cells in nasopharyngeal-associated lymphoreticular tissue
Y Hagiwara et al.
JOURNAL OF IMMUNOLOGY (2003)
Infectious disease risk in the elderly
BS Bender
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA (2003)
Human B cells express a CD45 isoform that is siniflar to murine B220 and is downregulated with acquisition of the memory B-CeH marker CD27
JJH Bleesing et al.
CYTOMETRY PART B-CLINICAL CYTOMETRY (2003)
Lack of antibody production following immunization in old age:: Association with CD8+CD28- T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines
M Saurwein-Teissl et al.
JOURNAL OF IMMUNOLOGY (2002)
Effector and memory T-cell differentiation: Implications for vaccine development
SM Kaech et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals
JJ Goronzy et al.
JOURNAL OF VIROLOGY (2001)
Share Paper
