Related references
Note: Only part of the references are listed.Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-beta 2
Corinna Seliger et al.
CELL CYCLE (2016)
Metformin influences progression in diabetic glioblastoma patients
Sebastian Adeberg et al.
STRAHLENTHERAPIE UND ONKOLOGIE (2015)
Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells
Tarek H. Mouhieddine et al.
FRONTIERS IN NEUROSCIENCE (2015)
Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response
Julie Sesen et al.
PLOS ONE (2015)
Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling Glucose regulatory protein 78 and AMPK
Prabodh K. Kandala et al.
Oncotarget (2015)
Lithium chloride decreases proliferation and migration of C6 glioma cells harboring isocitrate dehydrogenase 2 mutant via GSK-3β
Yuejun Fu et al.
MOLECULAR BIOLOGY REPORTS (2014)
Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK
Xiaona Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current
Marta Gritti et al.
ONCOTARGET (2014)
Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: Dependence on glucose concentration and role of AMPK
James Sinnett-Smith et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
An ent-Kaurane Diterpenoid from Croton tonkinensis Induces Apoptosis by Regulating AMP-Activated Protein Kinase in SK-HEP1 Human Hepatocellular Carcinoma Cells
Young Hoon Sul et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2013)
LKB1 and AMPK and the cancer-metabolism link - ten years after
D. Grahame Hardie et al.
BMC BIOLOGY (2013)
Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells
Emelie Karnevi et al.
BMC CANCER (2013)
Association of metformin use with cancer incidence and mortality: A meta-analysis
Pengpeng Zhang et al.
CANCER EPIDEMIOLOGY (2013)
Metformin selectively affects human glioblastoma tumor-initiating cell viability A role for metformin-induced inhibition of Akt
Roberto Wuerth et al.
CELL CYCLE (2013)
Nilotinib Induces Autophagy in Hepatocellular Carcinoma through AMPK Activation
Hui-Chuan Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Modulation of adipose tissue inflammation by bioactive food compounds
Nalin Siriwardhana et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2013)
PPARγ REGULATES THE MITOCHONDRIAL DYSFUNCTION IN HUMAN NEURAL STEM CELLS WITH TUMOR NECROSIS FACTOR ALPHA
M-C. Chiang et al.
NEUROSCIENCE (2013)
Metformin Inhibits the Growth of Human Pancreatic Cancer Xenografts
Krisztina Kisfalvi et al.
PANCREAS (2013)
AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity
H. T. Kwan et al.
PLOS ONE (2013)
Lithium Inhibits Tumorigenic Potential of PDA Cells through Targeting Hedgehog-GLI Signaling Pathway
Zhonglu Peng et al.
PLOS ONE (2013)
Low Concentrations of Metformin Selectively Inhibit CD133+ Cell Proliferation in Pancreatic Cancer and Have Anticancer Action
Shanmiao Gou et al.
PLOS ONE (2013)
Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs
Bruna Corominas-Faja et al.
AGING-US (2012)
Magnolol-Induced Apoptosis in HCT-116 Colon Cancer Cells Is Associated with the AMP-Activated Protein Kinase Signaling Pathway
Jun Beom Park et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2012)
Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells
Di Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells
Giovanni Vitale et al.
BIOTECHNOLOGY ADVANCES (2012)
Real-imaging cDNA-AFLP transcript profiling of pancreatic cancer patients: Egr-1 as a potential key regulator of muscle cachexia
Alexander Skorokhod et al.
BMC CANCER (2012)
An extract of chokeberry attenuates weight gain and modulates insulin, adipogenic and inflammatory signalling pathways in epididymal adipose tissue of rats fed a fructose-rich diet
Bolin Qin et al.
BRITISH JOURNAL OF NUTRITION (2012)
Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells
Bin Bao et al.
CANCER PREVENTION RESEARCH (2012)
AMPK Promotes p53 Acetylation via Phosphorylation and Inactivation of SIRT1 in Liver Cancer Cells
Chi-Wai Lee et al.
CANCER RESEARCH (2012)
Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice
Asuka Shiota et al.
CARDIOVASCULAR DIABETOLOGY (2012)
Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells
Weiguang Li et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2012)
Reduction of renal lipid content and proteinuria by a PPAR-γ agonist in a rat model of angiotensin II-induced hypertension
Aiko Sakamoto et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
The Influence of Type 2 Diabetes and Glucose-Lowering Therapies on Cancer Risk in the Taiwanese
Ming-Chia Hsieh et al.
EXPERIMENTAL DIABETES RESEARCH (2012)
Effect of lithium chloride and antineoplastic drugs on survival and cell cycle of androgen-dependent prostate cancer LNCap cells
Vajihe Azimian-Zavareh et al.
INDIAN JOURNAL OF PHARMACOLOGY (2012)
Promotion of adiponectin multimerization by emodin: A novel AMPK activator with PPARγ-agonist activity
Zhifen Chen et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2012)
Thiazolidenediones induce tumour-cell apoptosis through the Akt-GSK3ß pathway
H. Zhu et al.
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2012)
Diabetes mellitus correlates with increased risk of pancreatic cancer: A population-based cohort study in Taiwan
Kuan-Fu Liao et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2012)
Relationships Among Body Mass Index, Longitudinal Body Composition Alterations, and Survival in Patients With Locally Advanced Pancreatic Cancer Receiving Chemoradiation: A Pilot Study
Shalini Dalal et al.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2012)
Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells
Eun-Jeong Jung et al.
JOURNAL OF TOXICOLOGICAL SCIENCES (2012)
Cancer Risk Associated with Use of Metformin and Sulfonylurea in Type 2 Diabetes: A Meta-Analysis
Davide Soranna et al.
ONCOLOGIST (2012)
New-onset diabetes in pancreatic cancer: A study in the primary care setting
Gaurav Aggarwal et al.
PANCREATOLOGY (2012)
Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells
Toran Sanli et al.
PLOS ONE (2012)
Identification of an Annonaceous Acetogenin Mimetic, AA005, as an AMPK Activator and Autophagy Inducer in Colon Cancer Cells
Yong-Qiang Liu et al.
PLOS ONE (2012)
Activation of AMP-Activated Protein Kinase by 3,3′-Diindolylmethane (DIM) Is Associated with Human Prostate Cancer Cell Death In Vitro and In Vivo
Di Chen et al.
PLOS ONE (2012)
Improved insulin sensitivity after treatment with PPARγ and PPARα ligands is mediated by genetically modulated transcripts
Neda Rasouli et al.
PHARMACOGENETICS AND GENOMICS (2012)
Isoflavones as a smart curer for non-alcoholic fatty liver disease and pathological adiposity via ChREBP and Wnt signaling
Mi-Hyun Kim et al.
PREVENTIVE MEDICINE (2012)
Cachexia but not obesity worsens the postoperative outcome after pancreatoduodenectomy in pancreatic cancer
Thomas Pausch et al.
SURGERY (2012)
Silencing of Twist1 sensitizes NSCLC cells to cisplatin via AMPK-activated mTOR inhibition
H-O Jin et al.
CELL DEATH & DISEASE (2012)
Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
W-Y Shi et al.
CELL DEATH & DISEASE (2012)
Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK
Atsushi Sato et al.
STEM CELLS TRANSLATIONAL MEDICINE (2012)
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis
Arumugam Nagalingam et al.
BREAST CANCER RESEARCH (2012)
Nutritional Limitation Sensitizes Mammalian Cells to GSK-3β Inhibitors and Leads to Growth Impairment
Paola de Candia et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice
Alex Morrison et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
PPAR-γ and AMPK - Advantageous targets for myocardial ischemia/reperfusion therapy
Alex Morrison et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Global Cancer Statistics
Ahmedin Jemal et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2011)
Troglitazone, a PPAR agonist, inhibits human prostate cancer cell growth through inactivation of NFκB via suppression of GSK-3β expression
Jung Ok Ban et al.
CANCER BIOLOGY & THERAPY (2011)
Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells
Jorge Humberto Tapia-Perez et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Adiponectin Is Required for PPARγ-Mediated Improvement of Endothelial Function in Diabetic Mice
Wing Tak Wong et al.
CELL METABOLISM (2011)
Time-varying incidence of cancer after the onset of type 2 diabetes: evidence of potential detection bias
J. A. Johnson et al.
DIABETOLOGIA (2011)
The impact of type 2 diabetes and antidiabetic drugs on cancer cell growth
Yin-Hsun Feng et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
Modulation of the Development of Human Monocyte-Derived Dendritic Cells by Lithium Chloride
Ko-Jiunn Liu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice
Eleni Maniati et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Pioglitazone upregulates adiponectin receptor 2 in 3T3-L1 adipocytes
Akihiro Kudoh et al.
LIFE SCIENCES (2011)
Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced bya high-fat diet in nonalcoholic steatohepatitis
Gianluca Svegliati-Baroni et al.
LIVER INTERNATIONAL (2011)
BH3 mimetics activate multiple pro-autophagic pathways
S. A. Malik et al.
ONCOGENE (2011)
Pancreatogenic Diabetes: Special Considerations for Management
YunFeng Cui et al.
PANCREATOLOGY (2011)
Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis
Andrea DeCensi et al.
CANCER PREVENTION RESEARCH (2010)
Suppression of NF-κB and GSK-3β is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone
Jung Ok Ban et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2010)
Inverse association of PPARγ agonists use and high grade glioma development
Christian Grommes et al.
JOURNAL OF NEURO-ONCOLOGY (2010)
Inhibition of Growth in Medullary Thyroid Cancer Cells with Histone Deacetylase Inhibitors and Lithium Chloride
Joel T. Adler et al.
JOURNAL OF SURGICAL RESEARCH (2010)
ZM336372 Induces Apoptosis Associated with Phosphorylation of GSK-3β in Pancreatic Adenocarcinoma Cell Lines
Dustin Deming et al.
JOURNAL OF SURGICAL RESEARCH (2010)
Pancreatic cancerrelated cachexia: influence on metabolism and correlation to weight loss and pulmonary function
Jeannine Bachmann et al.
BMC CANCER (2009)
Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor γ synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells
Wei-Hao Sun et al.
CANCER LETTERS (2009)
Metformin Disrupts Crosstalk between G Protein-Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth
Krisztina Kisfalvi et al.
CANCER RESEARCH (2009)
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
C. J. Currie et al.
DIABETOLOGIA (2009)
Personalized Medicine for Pancreatic Cancer: A Step in the Right Direction
Andrew H. Ko et al.
GASTROENTEROLOGY (2009)
Antidiabetic Therapies Affect Risk of Pancreatic Cancer
Donghui Li et al.
GASTROENTEROLOGY (2009)
PPARγ and RXRγ ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models
Alessio Papi et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Post-Transcriptional Regulation of Cadherin-11 Expression by GSK-3 and β-Catenin in Prostate and Breast Cancer Cells
Anne K. Farina et al.
PLOS ONE (2009)
GSK3β Regulates Differentiation and Growth Arrest in Glioblastoma
Serdar Korur et al.
PLOS ONE (2009)
Knockin of mutant PIK3CA activates multiple oncogenic pathways
John P. Gustin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor γ involves angiogenesis inhibition
Yu-Wei Dong et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2009)
Inhibition of peroxisome proliferator-activated receptor γ activity suppresses pancreatic cancer cell motility
Atsushi Nakajima et al.
CANCER SCIENCE (2008)
Peroxisome Proliferator-Activated Receptor γ Agonists as Insulin Sensitizers: From the Discovery to Recent Progress
Nobuo Cho et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)
STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3β
Akira Moh et al.
DIABETES (2008)
New Drugs for Type 2 Diabetes Mellitus What is their Place in Therapy?
Andrew J. Krentz et al.
DRUGS (2008)
Anti-tumour activity of CS-7017, a selective peroxisome proliferator-activated receptor gamma agonist of thiazolidinedione class, in human tumour xenografts and a syngeneic tumour implant model
Naomi Shimazaki et al.
EUROPEAN JOURNAL OF CANCER (2008)
Pancreatic cancer-associated diabetes mellitus: Prevalence and temporal association with diagnosis of cancer
Suresh T. Chari et al.
GASTROENTEROLOGY (2008)
Cachexia worsens prognosis in patients with resectable pancreatic cancer
Jeannine Bachmann et al.
JOURNAL OF GASTROINTESTINAL SURGERY (2008)
Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3′-indoly)-1-(p-substituted phenyl)methanes
Ping Lei et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3
Michal O. Nowicki et al.
NEURO-ONCOLOGY (2008)
Lithium inhibits proliferation of human esophageal cancer cell line Eca-109 by inducing a G2/M cell cycle arrest
Jin-Sheng Wang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
Metformin induces apoptosis of pancreatic cancer cells
Luo-Wei Wang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo
Claire M. Edwards et al.
BLOOD (2008)
2-Cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor γ in colon and pancreatic cancer cells
Sudhakar Chintharlapalli et al.
CARCINOGENESIS (2007)
Suppression of N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters by pioglitazone, a ligand of peroxisome proliferator-activated receptor γ
Yoshito Takeuchi et al.
CARCINOGENESIS (2007)
Glitazones induce astroglioma cell death by releasing reactive oxygen species from mitochondria:: Modulation of cytotoxicity by nitric oxide
Jose M. Perez-Ortiz et al.
MOLECULAR PHARMACOLOGY (2007)
Inactivation of glycogen synthase kinase-3β, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells
Muthusamy Kunnimalaiyaan et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Pancreatic cancer in type 1 and young-onset diabetes: systematic review and meta-analysis
R. J. Stevens et al.
BRITISH JOURNAL OF CANCER (2007)
Pancreatic cancer-derived S-100A8 N-terminal peptide: A diabetes cause?
Daniela Basso et al.
CLINICA CHIMICA ACTA (2006)
Glycogen synthase kinase-3β positively regulates the proliferation of human ovarian cancer cells
Qi Cao et al.
CELL RESEARCH (2006)
Activation of peroxisome proliferator-activated receptor-γ decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system
H Sawai et al.
MOLECULAR CANCER RESEARCH (2006)
Annual report to the Nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment
BK Edwards et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2005)
Review article: anorexia and cachexia in gastrointestinal cancer
J Ockenga et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2005)
Role of mononuclear cells and inflammatory cytokines in pancreatic cancer-related cachexia
ME Martignoni et al.
CLINICAL CANCER RESEARCH (2005)
Type-II diabetes and pancreatic cancer:: a meta-analysis of 36 studies
R Huxley et al.
BRITISH JOURNAL OF CANCER (2005)
Proteomic characterization of harvested pseudopodia with differential gel electrophoresis and specific antibodies
ME Beckner et al.
LABORATORY INVESTIGATION (2005)
Cytokines in pancreatic carcinoma - Correlation with phenotypic characteristics and prognosis
B Ebrahimi et al.
CANCER (2004)
Peroxisome proliferator-activated receptor γ-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins
J Hong et al.
ENDOCRINOLOGY (2004)
Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARγ independent mechanisms
A Galli et al.
GUT (2004)
Glycogen synthase kinase-3β activity is required for androgen-stimulated gene expression in prostate cancer
XB Liao et al.
ENDOCRINOLOGY (2004)
Inhibition of cell invasion and morphological change by troglitazone in human pancreatic cancer cells
W Motomura et al.
JOURNAL OF GASTROENTEROLOGY (2004)
WNT7a induces E-cadherin in lung cancer cells
T Ohira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium - Evidence for autoregulation of GSK-3
F Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ligands for PPAR gamma and RAR cause induction of growth inhibition and apoptosis in human glioblastomas
CB Zang et al.
JOURNAL OF NEURO-ONCOLOGY (2003)
Lithium chloride at a therapeutic concentration reduces Ca2+ response in protein kinase C down-regulated human astrocytoma cells
M Kurita et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Growth inhibition and differentiation of pancreatic cancer cell lines by PPAR gamma ligand troglitazone
S Kawa et al.
PANCREAS (2002)
Inhibition of GSK-3 selectively reduces glucose-B-phosphatase and phosphoenolpyruvate carboxykinase gene expression
PA Lochhead et al.
DIABETES (2001)
Pancreatic resection: Effects on glucose metabolism
LA Slezak et al.
WORLD JOURNAL OF SURGERY (2001)
Activation of peroxisome proliferator-activated receptor gamma inhibits the growth of human pancreatic cancer
T Sasaki et al.
PATHOBIOLOGY (2001)
Physiological concentrations of insulin augment pancreatic cancer cell proliferation and glucose utilization by activating MAP kinase, PI3 kinase and enhancing GLUT-1 expression
XZ Ding et al.
PANCREAS (2000)
Early diagnosis and treatment of pancreatic dysplasia in patients with a family history of pancreatic cancer (vol 131, pg 247, 1999)
TA Brentnall et al.
ANNALS OF INTERNAL MEDICINE (2000)
Share Paper
