Journal
BIOCHEMICAL ENGINEERING JOURNAL
Volume 105, Issue -, Pages 264-272Publisher
ELSEVIER
DOI: 10.1016/j.bej.2015.09.021
Keywords
Biomedical; Biosynthesis; Cytotoxicity; DNA; Nanoparticles; Optimisation
Funding
- Department of Biotechnology (DBT), Government of India
Ask authors/readers for more resources
In the present paper, a facile synthesis of gold nanoparticles is reported with leaf and stem extract of Hibiscus sabdariffa. Structural features of as synthesized nanoparticles are characterized by UV-vis spectroscopy, XRD, FTIR, and XPS. Morphology of the above synthesized gold nanoparticles is investigated by electron microscopy. The stability of the nanoparticles is studied in different concentrations of glucose which suggested their possible application under hyperglycemic condition. As synthesized nanoparticles has shown selective toxicity towards U87 glioblastoma multiforme cell line under normal and hyperglycemic condition, indicating their potential to be used in the development of value-added products in the biochemical industries. The possible mode of activity of the above nanoparticles has been studied by in vitro molecular techniques. (C) 2015 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available