Journal
ADVANCED HEALTHCARE MATERIALS
Volume 8, Issue 19, Pages -Publisher
WILEY
DOI: 10.1002/adhm.201900742
Keywords
hierarchical vasculatures; microvasculatures; prevascularization; tissue-engineered vascular grafts; vascular tissue engineering
Funding
- Australian Commonwealth Government Research Training Program
- Australian Research Council
- National Health and Medical Research Council
Ask authors/readers for more resources
Impaired or damaged blood vessels can occur at all levels in the hierarchy of vascular systems from large vasculatures such as arteries and veins to meso- and microvasculatures such as arterioles, venules, and capillary networks. Vascular tissue engineering has become a promising approach for fabricating small-diameter vascular grafts for occlusive arteries. Vascularized tissue engineering aims to fabricate meso- and microvasculatures for the prevascularization of engineered tissues and organs. The ideal small-diameter vascular graft is biocompatible, bridgeable, and mechanically robust to maintain patency while promoting tissue remodeling. The desirable fabricated meso- and microvasculatures should rapidly integrate with the host blood vessels and allow nutrient and waste exchange throughout the construct after implantation. A number of techniques used, including engineering-based and cell-based approaches, to fabricate these synthetic vasculatures are herein explored, as well as the techniques developed to fabricate hierarchical structures that comprise multiple levels of vasculature.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available