Journal
SAUDI PHARMACEUTICAL JOURNAL
Volume 27, Issue 7, Pages 990-999Publisher
ELSEVIER
DOI: 10.1016/j.jsps.2019.08.001
Keywords
Temperature-sensitive; Hydrogels; Biotherapeutic molecules
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To date, a variety of delivery systems based on organic or inorganic materials have been investigated. Among them, hydrogels have become one of the most promising field in drug delivery system due to their unique properties. Temperature-sensitive hydrogels, which gelation at physiological temperature, gift the delivery system with excellent spatial and temporal control, and have a widely application in drug delivery, tissue engineering, imaging, and wound dressing. This review provides a brief overview on the concept and classification of temperature-sensitive hydrogels, and covers the application of temperature-sensitive gel systems in delivery of biotherapeutic molecules. (C) 2019 Production and hosting by Elsevier B.V. on behalf of King Saud University.
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