4.6 Editorial Material

Acne: Transient Arrest in the Homeostatic Host-Microbiota Dialog?

Journal

TRENDS IN IMMUNOLOGY
Volume 40, Issue 10, Pages 873-876

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.it.2019.08.006

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Categories

Funding

  1. Hungarian Research Grant [NKFIH K-128250]
  2. European Union
  3. European Regional Development Fund
  4. European Social Fund
  5. Janos Bolyai research scholarship of the Hungarian Academy of Sciences
  6. New National Excellence Program of the Ministry of Human Capacities [UNKP-18-4]
  7. [GINOP-2.3.2-15-2016-00050]
  8. [EFOP-3.6.1-16-2016-00022]

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We propose that acne vulgaris represents a naturally developing, transient inflammatory interaction of adolescent facial skin with its new microbial/chemical milieu (Cutibacterium acnes, sebum), replacing a state of previous childhood skin homeostasis. This concept might explain why acne is characterized by strong regional and age specificity, prevalent occurrence, and resolution.

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