Fast gas chromatography-mass spectrometry: A review of the last decade

The present contribution is an overview of the state-of-the-art of fast gas chromatography coupled to mass spectrometry (fast GC-MS). Specifically, published papers over the last ten years (2009-December 2018) have been considered. Several aspects of fast GC-MS are here critically discussed, focusing on four of the most common routes to shorten GC analyses times: micro-bore columns, narrow-bore columns, low-pressure outlet conditions, and resistive heating. Moreover, great attention has been dedicated to mass spectrometry coupling. Finally, the strong and weak points of each high-speed GC approach are also highlighted. (C) 2019 Elsevier B.V. All rights reserved.