4.2 Article

Effect of lemon grass extract against methyl methanesulfonate-induced toxicity

Journal

TOXIN REVIEWS
Volume 40, Issue 4, Pages 1172-1186

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/15569543.2019.1657152

Keywords

Drosophila; methyl methanesulfonate; lemon grass; toxicity; hsp70

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The study found that lemon grass extract has a protective function against MMS-induced toxicity in transgenic Drosophila larvae.
The present study aims to study the effect of lemon grass extract (LGE) (Cymbopogon flexuosus) against the methyl methanesulfonate (MMS)-induced toxicity in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9. The third instar larvae were allowed to feed on diet having 10 mu M of MMS alone and along with LGE concentrations of 1.6 x 10(-3) g/ml; 3.2 x 10(-3) g/ml; 4.9 x 10(-3) g/ml and 6.6 x 10(-3) g/ml established in food for 24 h before performing the assays. The present study supports protective function of lemon grass against MMS-induced toxicity.

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