Journal
TETRAHEDRON
Volume 75, Issue 33, Pages 4620-4625Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2019.07.005
Keywords
Norsesterterpenoid; Cyclic peroxide; Sponge; Marine natural products; Cytotoxicity
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Two new norsesterterpenoid cyclic peroxides, trunculins X and Y, were isolated from an Okinawan sponge Sigmosceptrella sp. Their structures were determined by spectroscopic analyses on intact molecules and derivatives and also by crystallographic study. The compounds showed cytotoxicity in a range of IC50 0.32-20 mu M against three cell lines. (C) 2019 Elsevier Ltd. All rights reserved.
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