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Application of Cope rearrangement in synthesis

Journal

SYNTHETIC COMMUNICATIONS
Volume 49, Issue 22, Pages 3101-3111

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2019.1657460

Keywords

Cope rearrangement; natural products; synthesis; application

Funding

  1. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry [2015-1098]
  2. Chongqing Key Research Project of Basic Science & Frontier Technology, China [cstc2017jcyjBX0012]
  3. Foundation Project of Chongqing Normal University, China [14XYY020]
  4. Chongqing General Research Program of Basic Research and Frontier Technology, China [cstc2015jcyjA10054]
  5. Chongqing Normal University Postgraduate's Research and Innovation Project, China [YKC17004]

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Cope rearrangement is one of the pericyclic reactions in many organic rearrangements. It has high stereoselectivity and has been widely used in organic synthesis chemistry. Herein, the discovery, mechanism, and application of Cope rearrangement were analyzed and discussed.

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