4.4 Article

Acid-Catalysed Rearrangement of the Sandfly Pheromone Sobralene to Verticillenes, Consolidating its Relationship inter alia to the Taxanes and Phomactins

Journal

SYNLETT
Volume 30, Issue 16, Pages 1899-1903

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0039-1690131

Keywords

pheromone; sandfly; verticillenes; metabolite; taxadiene

Funding

  1. School of Chemistry at The University of Nottingham

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The sex-aggregation pheromone sobralene produced by the sandfly Lutzomyia longipalpis is isomerised to verticillenes in the presence of mild acid, thereby providing credence to the proposal that sobralene is a likely shunt metabolite of the taxadiene synthase cascade.

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