Journal
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume 12, Issue -, Pages 496-504Publisher
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.12.49
Keywords
copper; modular synthesis; triarylmethanes
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Funding
- UGC
- UGC-SAP
- CSIR
- DST-FIST
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A facile and modular synthesis of triarylmethanes was achieved in good yield via a two-step sequence in which the final step is the copper(II)-catalyzed arylation of diarylmethanols with arylboronic acids. By using this protocol a variety of symmetrical and unsymmetrical triarylmethanes were synthesized. As an application of the newly developed methodology, we demonstrate a high-yielding synthesis of the triarylmethane intermediate towards an anti-breast-cancer drug candidate.
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