Journal
SMALL
Volume 16, Issue 27, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.201902464
Keywords
biomedical applications; cargo transportation; guidance strategies; micro; nanomotors; self-propulsion
Categories
Funding
- National Natural Science Foundation of China [51802060]
- Shenzhen Peacock Innovation Project [KQJSCX20170726104623185]
- Generalitat de Catalunya [CTQ2015-68879-R, CTQ2015-72471-EXP]
- Spanish MINECO [CTQ2015-68879-R, CTQ2015-72471-EXP]
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Micro/nanomotors (MNMs) are miniaturized machines that can perform assigned tasks at the micro/nanoscale. Over the past decade, significant progress has been made in the design, preparation, and applications of MNMs that are powered by converting different sources of energy into mechanical force, to realize active movement and fulfill on-demand tasks. MNMs can be navigated to desired locations with precise controllability based on different guidance mechanisms. A considerable research effort has gone into demonstrating that MNMs possess the potential of biomedical cargo loading, transportation, and targeted release to achieve therapeutic functions. Herein, the recent advances of self-propelled MNMs for on-demand biomedical cargo transportation, including their self-propulsion mechanisms, guidance strategies, as well as proof-of-concept studies for biological applications are presented. In addition, some of the major challenges and possible opportunities of MNMs are identified for future biomedical applications in the hope that it may inspire future research.
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