4.8 Article

Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation

Journal

SCIENCE TRANSLATIONAL MEDICINE
Volume 11, Issue 508, Pages -

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scitranslmed.aax8251

Keywords

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Funding

  1. NIH [R01-EB020539, R01-HL131829, R01-EB025985, R56-AI145435, DP5-OD26386]
  2. Department of Defense's Congressionally Directed Medical Research Programs [PR-171338P1]
  3. Burroughs Wellcome Fund Career Award for Medical Scientists
  4. Johns Hopkins All Children's Hospital Foundation Institutional Grant Program

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Clinical diagnostic tools requiring direct sample testing cannot be applied to infections deep within the body, and clinically available imaging tools lack specificity. New approaches are needed for early diagnosis and monitoring of bacterial infections and rapid detection of drug-resistant organisms. Molecular imaging allows for longitudinal, noninvasive assessments and can provide key information about infectious processes deep within the body.

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