Journal
RECORDS OF NATURAL PRODUCTS
Volume 14, Issue 1, Pages 77-82Publisher
ACG PUBLICATIONS
DOI: 10.25135/rnp.139.19.04.1263
Keywords
Tricholoma caligatum; iNOS; NF-kappa B; anti-inflammatory; lascivol
Categories
Funding
- Scientific and Technological Research Council of Turkey [TUBITAK BIDEB-2214-A]
- TUBITAK [1001-113R012]
Ask authors/readers for more resources
Tricholoma caligatum (Viv.) Ricken is an edible mushroom that belongs to matsutake group. The first chemical investigation of the three different extracts of Tricholoma caligatum resulted in two new compounds, 8-demethoxylascivol (1) and 8-epi-lascivol (2) and six known compounds, lascivol (3), trametenolic acid (4), ergosterol (5), ergosterol peroxide (6), 5 alpha, 6 alpha-epoxyergosterol (7), and cerebroside B (8). Their structures were elucidated by spectroscopic analyses including 1D and 2D NMR data. The biological activities of all the compounds were evaluated toward multiple targets related to inflammation and metabolic disorder such as NF-kappa B, iNOS and ROS. The findings of this study reveal that the edible mushroom Tricholoma caligatum could be a potential source for anti-inflammatory bioactive metabolites.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available