Journal
PROGRESS IN CARDIOVASCULAR DISEASES
Volume 62, Issue 4, Pages 298-302Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.pcad.2019.07.003
Keywords
Diabetes mellitus; Type 2 diabetes mellitus; Heart failure; Chronic kidney disease; Diabetic kidney disease; Cardiovascular disease
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The prevalence of Type 2 diabetes mellitus (T2DM) has reached pandemic proportions. T2DM frequently causes macrovascular and/or microvascular pathologic changes and thereby increases the risks for the development of myocardial infarction, heart failure, stroke, renal failure, and reduced survival. This article describes the important interactions between T2DM, heart failure, and renal dysfunction, forming vicious circles. The interruption of these circles represents important therapeutic goals. (C) 2019 Elsevier Inc. All rights reserved.
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