Journal
ORGANIC LETTERS
Volume 21, Issue 16, Pages 6285-6288Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b02169
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Funding
- National Natural Science Foundation of China [21625203, 21871126]
- Opening Fund of KLCBTCMR, Ministry of Education [KLCBTCMR18-02]
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A new, general copper-catalyzed oxidative tandem [4+2] cycloaddition of alpha-(N-arylamino) carbonyl compounds with aryl alkenes to produce highly substituted quinolines has been developed, which allows the formation of three new C-C bonds through a sequence of multiple C-H functionalizations, annulation, and [1,2]-aryl shifts.
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