Journal
ORGANIC LETTERS
Volume 21, Issue 16, Pages 6397-6402Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b02308
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Funding
- Science & Technology Department of Sichuan Province [2019YJ0339]
- NSFC [21572083, 21572183, 21772158, 21801208, 21825104]
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The first copper hydride (CuH)-catalyzed asymmetric 1,6-conjugate reduction of p-quinone methides is reported. This protocol provides a new method to access a variety of triarylmethanes and 1,1,2-triarylethanes in good yields with excellent enantioselectivities and broad functional group tolerance.
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