4.8 Article

Sulfhydryl-Directed Iridium-Catalyzed C-H/Diazo Coupling and Tandem Annulation of Naphthalene-1-thiols

Journal

ORGANIC LETTERS
Volume 21, Issue 17, Pages 7000-7003

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b02581

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Funding

  1. National Natural Science Foundation of China [21672108]

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The first sulfhydryl-directed iridium-catalyzed C-H/diazo coupling and tandem annulation of naphthalene-1-thiols has been developed. The framework of naphtho[1,8-bc]-thiopyrans was constructed in a one-step reaction with good yields. This transformation provides a practical synthetic route for the widely used naphtho[1,8-bc]thiopyran derivatives.

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