Journal
ORGANIC LETTERS
Volume 21, Issue 19, Pages 7970-7975Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b02948
Keywords
-
Categories
Funding
- Austrian COMET Program by the Austrian Federal Ministry of Transport, Innovation and Technology (BMVIT) [862766]
- Austrian COMET Program by the Austrian Federal Ministry of Science, Research and Economy (BMWFW) [862766]
- Austrian COMET Program by the State of Styria (Styrian Funding Agency SFG) [862766]
Ask authors/readers for more resources
While several trifluoromethylation reactions involving the electrochemical generation of CF3 radicals via anodic oxidation have been reported, the alternative cathodic, reductive radical generation has remained elusive. Herein, the first cathodic trifluoromethylation of arenes and heteroarenes is reported. The method is based on the electrochemical reduction of an unstable triflyltriethylammonium complex generated in situ from inexpensive triflyl chloride and triethylamine, which produces CF3 radicals that are trapped by the arenes on the cathode surface.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available