Journal
NUCLEIC ACIDS RESEARCH
Volume 47, Issue 15, Pages 7842-7856Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkz621
Keywords
-
Categories
Funding
- National Key Research and Development Program [2016YFC0901603]
- China 863 Program [2015AA020108]
- State Key Laboratory of Protein and Plant Gene Research
- Beijing Advanced Innovation Center for Genomics (ICG) at Peking University
- National Program for Support of Top-notch Young Professionals
Ask authors/readers for more resources
Long noncoding RNAs (lncRNAs) are emerging as key regulators of multiple essential biological processes involved in physiology and pathology. By analyzing the largest compendium of 14,166 samples from normal and tumor tissues, we significantly expand the landscape of human long noncoding RNA with a high-quality atlas: RefLnc (Reference catalog of LncRNA). Powered by comprehensive annotation across multiple sources, RefLnc helps to pinpoint 275 novel intergenic lncRNAs correlated with sex, age or race as well as 369 novel ones associated with patient survival, clinical stage, tumor metastasis or recurrence. Integrated in a user-friendly online portal, the expanded catalog of human lncRNAs provides a valuable resource for investigating lncRNA function in both human biology and cancer development.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
