Related references
Note: Only part of the references are listed.Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization
Kun Liu et al.
AUTOPHAGY (2015)
Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis
Roni Nowarski et al.
CELL (2015)
PROSTATE CANCER 4 BIG QUESTIONS
Richard Hodson
NATURE (2015)
Leptin-Mediated Increases in Catecholamine Signaling Reduce Adipose Tissue Inflammation via Activation of Macrophage HDAC4
Bing Luan et al.
CELL METABOLISM (2014)
An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice
Na-Ri Shin et al.
GUT (2014)
Autophagy-a key player in cellular and body metabolism
Kook Hwan Kim et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes
Yu-Mi Lim et al.
NATURE COMMUNICATIONS (2014)
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
Sandra Cabrera et al.
AUTOPHAGY (2013)
Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation
Kook Hwan Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
The Origins and Drivers of Insulin Resistance
Andrew M. F. Johnson et al.
CELL (2013)
Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense
Julia Farache et al.
IMMUNOLOGY AND CELL BIOLOGY (2013)
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
Takuma Misawa et al.
NATURE IMMUNOLOGY (2013)
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
Kook Hwan Kim et al.
NATURE MEDICINE (2013)
Autophagy Links Inflammasomes to Atherosclerotic Progression
Babak Razani et al.
CELL METABOLISM (2012)
Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice
W. Quan et al.
DIABETOLOGIA (2012)
Role of Hypothalamic Proopiomelanocortin Neuron Autophagy in the Control of Appetite and Leptin Response
Wenying Quan et al.
ENDOCRINOLOGY (2012)
Dual Priming Oligonucleotides for Broad-Range Amplification of the Bacterial 16S rRNA Gene Directly from Human Clinical Specimens
Oyvind Kommedal et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2012)
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Chong-Shan Shi et al.
NATURE IMMUNOLOGY (2012)
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
Saswata Talukdar et al.
NATURE MEDICINE (2012)
Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance
Durba Pal et al.
NATURE MEDICINE (2012)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance
Susmita Kaushik et al.
CELL METABOLISM (2011)
Targeting Curcusomes to Inflammatory Dendritic Cells Inhibits NF-κB and proves Insulin Resistance in Obese Mice
Suman Kumar Yekollu et al.
DIABETES (2011)
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
Jacques Amar et al.
EMBO MOLECULAR MEDICINE (2011)
Elimination of the NLRP3-ASC Inflammasome Protects against Chronic Obesity-Induced Pancreatic Damage
Yun-Hee Youm et al.
ENDOCRINOLOGY (2011)
Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases
Warren Strober et al.
GASTROENTEROLOGY (2011)
The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
Yun-Gi Kim et al.
IMMUNITY (2011)
Th17 cells in inflammation
Akihiro Kimura et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2011)
A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou et al.
NATURE (2011)
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
Haitao Wen et al.
NATURE IMMUNOLOGY (2011)
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
Bolormaa Vandanmagsar et al.
NATURE MEDICINE (2011)
ISLET AMYLOID POLYPEPTIDE, ISLET AMYLOID, AND DIABETES MELLITUS
Per Westermark et al.
PHYSIOLOGICAL REVIEWS (2011)
Inflammasome is a central player in the induction of obesity and insulin resistance
Rinke Stienstra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine
Ken Cadwell et al.
CELL (2010)
Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance
Ling Yang et al.
CELL METABOLISM (2010)
XOMA 052, an Anti-IL-1β Monoclonal Antibody, Improves Glucose Control and β-Cell Function in the Diet-Induced Obesity Mouse Model
Alexander M. Owyang et al.
ENDOCRINOLOGY (2010)
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
Christian Bauer et al.
GUT (2010)
The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
Md. Hasan Zaki et al.
IMMUNITY (2010)
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1 beta in type 2 diabetes
Seth L. Masters et al.
NATURE IMMUNOLOGY (2010)
Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice
Myoung Sook Han et al.
DIABETES (2009)
Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease
S. Brand
GUT (2009)
Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling
Yeonseok Chung et al.
IMMUNITY (2009)
Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-induced Colitis
Philip Alex et al.
INFLAMMATORY BOWEL DISEASES (2009)
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice
Anurag Kumar Singh et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Autophagy regulates lipid metabolism
Rajat Singh et al.
NATURE (2009)
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
Markus Feuerer et al.
NATURE MEDICINE (2009)
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
Yong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
Corinne Cayrol et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Autophagosome-independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens
Zijiang Zhao et al.
CELL HOST & MICROBE (2008)
Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
Hye Seung Jung et al.
CELL METABOLISM (2008)
Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet
Chie Ebato et al.
CELL METABOLISM (2008)
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
Qizhi Tang et al.
IMMUNITY (2008)
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
Xuexian O. Yang et al.
IMMUNITY (2008)
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
Tatsuya Saitoh et al.
NATURE (2008)
Adipocyte death, adipose tissue remodeling, and obesity complications
Katherine J. Strissel et al.
DIABETES (2007)
Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease
Dunecan C. O. Massey et al.
AUTOPHAGY (2007)
Toll-like receptor 2 senses β-cell death and contributes to the initiation of autoimmune diabetes
Hun Sik Kim et al.
IMMUNITY (2007)
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani et al.
DIABETES (2007)
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
Claus M. Larsen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression
Charles D. Searles
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis
Christoph Becker et al.
JOURNAL OF IMMUNOLOGY (2006)
IL-1β breaks tolerance through expansion of CD25+ effector T cells
Brendan J. O'Sullivan et al.
JOURNAL OF IMMUNOLOGY (2006)
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
MG Netea et al.
NATURE MEDICINE (2006)
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
D Yen et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody
IJ Fuss et al.
INFLAMMATORY BOWEL DISEASES (2006)
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
S Cinti et al.
JOURNAL OF LIPID RESEARCH (2005)
Essential role of STAT1 in caspase-independent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway
HS Kim et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
KF Petersen et al.
SCIENCE (2003)
IL-1β-converting enzyme (caspase-1) in intestinal inflammation
B Siegmund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
IL-6 is required for the development of Th1 cell-mediated murine colitis
M Yamamoto et al.
JOURNAL OF IMMUNOLOGY (2000)