4.8 Editorial Material

Doubling down on siRNAs in the brain

Related references

Note: Only part of the references are listed.
Article Medicine, General & Internal

Targeting Huntingtin Expression in Patients with Huntington's Disease

Sarah J. Tabrizi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Biotechnology & Applied Microbiology

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

Julia F. Alterman et al.

NATURE BIOTECHNOLOGY (2019)

Review Biochemistry & Molecular Biology

Metazoan MicroRNAs

David P. Bartel

Review Biotechnology & Applied Microbiology

Translation of MicroRNA-Based Huntingtin-Lowering Therapies from Preclinical Studies to the Clinic

Jana Miniarikova et al.

MOLECULAR THERAPY (2018)

Article Biochemistry & Molecular Biology

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

Matthew R. Hassler et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Neurosciences

Widespread suppression of huntingtin with convection-enhanced delivery of siRNA

David K. Stiles et al.

EXPERIMENTAL NEUROLOGY (2012)

Article Multidisciplinary Sciences

Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

M. DiFiglia et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

SQ Harper et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)