4.8 Article

CRISPR DNA base editors with reduced RNA off-target and self-editing activities

Related references

Note: Only part of the references are listed.
Letter Biotechnology & Applied Microbiology

CRISPResso2 provides accurate and rapid genome editing sequence analysis

Kendell Clement et al.

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

Julian Grunewald et al.

NATURE (2019)

Article Multidisciplinary Sciences

Analysis and minimization of cellular RNA editing by DNA adenine base editors

Holly A. Rees et al.

SCIENCE ADVANCES (2019)

Article Multidisciplinary Sciences

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Changyang Zhou et al.

NATURE (2019)

Article Biotechnology & Applied Microbiology

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction

Luke W. Koblan et al.

NATURE BIOTECHNOLOGY (2018)

Article Biotechnology & Applied Microbiology

Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion

Xiao Wang et al.

NATURE BIOTECHNOLOGY (2018)

Article Biotechnology & Applied Microbiology

An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities

Jason M. Gehrke et al.

NATURE BIOTECHNOLOGY (2018)

Article Multidisciplinary Sciences

Engineered CRISPR-Cas9 nuclease with expanded targeting space

Hiroshi Nishimasu et al.

SCIENCE (2018)

Review Genetics & Heredity

Base editing: precision chemistry on the genome and transcriptome of living cells

Holly A. Rees et al.

NATURE REVIEWS GENETICS (2018)

Article Biochemistry & Molecular Biology

Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes

Shraddha Sharma et al.

RNA BIOLOGY (2017)

Article Multidisciplinary Sciences

Programmable base editing of A.T to G.C in genomic DNA without DNA cleavage

Nicole M. Gaudelli et al.

NATURE (2017)

Article Multidisciplinary Sciences

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor et al.

NATURE (2016)

Article Biotechnology & Applied Microbiology

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Shengdar Q. Tsai et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Article Biochemistry & Molecular Biology

Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture

Nadin Rohland et al.

GENOME RESEARCH (2012)

Article Genetics & Heredity

A framework for variation discovery and genotyping using next-generation DNA sequencing data

Mark A. DePristo et al.

NATURE GENETICS (2011)

Article Biochemistry & Molecular Biology

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Aaron McKenna et al.

GENOME RESEARCH (2010)

Article Biochemistry & Molecular Biology

Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase

Jungwook Kim et al.

BIOCHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA

HC Losey et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli

J Wolf et al.

EMBO JOURNAL (2002)