Journal
MOLECULAR BIOLOGY AND EVOLUTION
Volume 36, Issue 12, Pages 2922-2924Publisher
OXFORD UNIV PRESS
DOI: 10.1093/molbev/msz185
Keywords
visualization; BLAST; comparative genomics; sequence analysis
Funding
- European Research Council
- United States Department of Energy [DE-SC0004632]
- Biotechnology and Biological Sciences Research Council [BB/K004204/1]
- Natural Environment Research Council [NE/L00626X/1]
- BBSRC [BB/K004204/1] Funding Source: UKRI
- NERC [NE/L00626X/1] Funding Source: UKRI
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Comparing newly obtained and previously known nucleotide and amino-acid sequences underpins modern biological research. BLAST is a well-established tool for such comparisons but is challenging to use on new data sets. We combined a user-centric design philosophy with sustainable software development approaches to create Sequenceserver, a tool for running BLAST and visually inspecting BLAST results for biological interpretation. Sequenceserver uses simple algorithms to prevent potential analysis errors and provides flexible text-based and visual outputs to support researcher productivity. Our software can be rapidly installed for use by individuals or on shared servers.
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