4.7 Article

Palladium-Catalyzed Coupling of Terminal Alkynes with Benzyl Ammonium Salts

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 84, Issue 18, Pages 12192-12197

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b01877

Keywords

-

Funding

  1. National Natural Science Foundation of China [21778025, 21762021]
  2. Science and Technology Project of Jiangxi Provincial Education Department [GJJ150297, GJJ150324]

Ask authors/readers for more resources

( )A highly efficient palladium-catalyzed Sonoga-shira coupling of benzylic ammonium salts with terminal alkynes is developed. This strategy provides a facile access to a series of internal alkyne derivatives in moderate to excellent yields via C-N bond cleavage and C(sp(3))-C(sp) bond formation. The broad substrate scope and high functional group tolerance make this reaction attractive for organic synthesis.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available