Journal
JOURNAL OF MAGNETIC RESONANCE IMAGING
Volume 52, Issue 2, Pages 369-379Publisher
WILEY
DOI: 10.1002/jmri.26911
Keywords
kidney; perfusion; dynamic contrast enhanced; arterial spin labeling; intra-voxel incoherent motion
Funding
- National Institutes of Health (NIH) [R01HL135242, R01DK109349]
Ask authors/readers for more resources
Renal perfusion can be quantitatively assessed by multiple magnetic resonance imaging (MRI) methods, including dynamic contrast enhanced (DCE), arterial spin labeling (ASL), and diffusion-weighted imaging with intravoxel incoherent motion (IVIM) analysis. In this review we summarize the advances in the field of renal-perfusion MRI over the past 5 years. The review starts with a brief introduction of relevant MRI methods, followed by a discussion of recent technical developments. In the main section of the review, we examine the clinical and preclinical applications for three disease populations: chronic kidney disease, renal transplant, and renal tumors. The DCE method has been routinely used for assessing renal tumors but not other renal diseases. As a noncontrast alternative, ASL was extensively explored in both preclinical and clinical applications and showed much promise. Protocol standardization for the methods is desperately needed, and then large-scale clinical trials for the methods can be initiated prior to their broad clinical use. Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available