Journal
JOURNAL OF MAGNETIC RESONANCE
Volume 305, Issue -, Pages 41-50Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jmr.2019.06.001
Keywords
Dissolution DNP; Real-time monitoring; analytical d-DNP
Funding
- European Research Council under the European Union's Horizon 2020 research and innovation program (ERC) [714519/HP4all, 801936/HYPROTIN, 801774/DINAMIX]
- French National Research Agency [ANR-17-ERC2-0011]
- Corsaire metabolomics core facility
- Agence Nationale de la Recherche (ANR) [ANR-17-ERC2-0011] Funding Source: Agence Nationale de la Recherche (ANR)
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Dissolution dynamic nuclear polarization (d-DNP) is a versatile method to enhance nuclear magnetic resonance (NMR) spectroscopy. It boosts signal intensities by four to five orders of magnitude thereby providing the potential to improve and enable a plethora of applications ranging from the real-time monitoring of chemical or biological processes to metabolomics and in-cell investigations. This perspectives article highlights possible avenues for developments and applications of d-DNP in biochemical and physicochemical studies. It outlines how chemists, biologists and physicists with various fields of interest can transform and employ d-DNP as a powerful characterization method for their research. (C) 2019 Elsevier Inc. All rights reserved.
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