Overview on Recent Approaches towards Synthesis of 2-Keto-annulated Oxazole Derivatives

In recent years, oxazole derivatives have emerged as one of the formidable groups of compounds in the field of medicinal chemistry and drug discovery. The titled compounds 2-keto-annulated oxazoles play an important role towards the medicinal aspects. There has been an appearance of a significant number of research articles and reviews to explore the wide utility of oxazole derivatives. However, till now, there has been no dedicated review published focusing on the synthesis of 2-keto-annulated oxazole derivatives. Herein, we have presented the recent protocols available in literature for the synthesis of 2-keto-annulated oxazoles and highlighted the advantages of these methods that would attract the attention of a broad range of readers in the chemistry community.