Related references
Note: Only part of the references are listed.Hypothalamic expression of the atypical chemokine receptor ACKR2 is involved in the systemic regulation of glucose tolerance
Milena Fioravante et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)
The proteostasis network and its decline in ageing
Mark S. Hipp et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Eating Rewards the Gears of the Clock
Jorge Mendoza
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2019)
CD1 is involved in diet-induced hypothalamic inflammation in obesity
Bruna Bombassaro et al.
BRAIN BEHAVIOR AND IMMUNITY (2019)
Leptin Signaling in the Arcuate Nucleus Reduces Insulin's Capacity to Suppress Hepatic Glucose Production in Obese Mice
Eglantine Balland et al.
CELL REPORTS (2019)
Overlapping Brain Circuits for Homeostatic and Hedonic Feeding
Mark A. Rossi et al.
CELL METABOLISM (2018)
Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity
Rodrigo S. Carraro et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2018)
The Unfolded Protein Response and Cell Fate Control
Claudio Hetz et al.
MOLECULAR CELL (2018)
Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
Veronica Eisner et al.
NATURE CELL BIOLOGY (2018)
POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels
Alexandre Caron et al.
ELIFE (2018)
Genetic identification of leptin neural circuits in energy and glucose homeostases
Jie Xu et al.
NATURE (2018)
Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity
Cristina Contreras et al.
DIABETES (2017)
Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype
Milena Fioravante et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Autophagy: The spotlight for cellular stress responses
Palaniyandi Ravanan et al.
LIFE SCIENCES (2017)
The cellular and molecular bases of leptin and ghrelin resistance in obesity
Huxing Cui et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
Toward a Wiring Diagram Understanding of Appetite Control
Mark L. Andermann et al.
NEURON (2017)
TNFα drives mitochondrial stress in POMC neurons in obesity
Chun-Xia Yi et al.
NATURE COMMUNICATIONS (2017)
Energy imbalance alters Ca2+ handling and excitability of POMC neurons
Lars Paeger et al.
ELIFE (2017)
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility
Martin Valdearcos et al.
CELL METABOLISM (2017)
Autophagy: An overview and its roles in cancer and obesity
Joe Antony Jacob et al.
CLINICA CHIMICA ACTA (2017)
Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control
Sara Ramirez et al.
CELL METABOLISM (2017)
DRP1 Suppresses Leptin and Glucose Sensing of POMC Neurons
Anna Santoro et al.
CELL METABOLISM (2017)
Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina
Kyle R. Biesecker et al.
JOURNAL OF NEUROSCIENCE (2016)
Autophagy proteins are modulated in the liver and hypothalamus of the offspring of mice with diet-induced obesity
Andressa Reginato et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2016)
The pathophysiology of defective proteostasis in the hypothalamus - from obesity to ageing
Claudia Cavadas et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Mitochondrial ROS Signaling in Organismal Homeostasis
Gerald S. Shadel et al.
CELL (2015)
Proteostasis control by the unfolded protein response
Claudio Hetz et al.
NATURE CELL BIOLOGY (2015)
Targeting endoplasmic reticulum stress in insulin resistance
Laia Salvado et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2015)
Mitochondrial dynamics and mitochondrial quality control
Hong-Min Ni et al.
REDOX BIOLOGY (2015)
Saturated Fatty Acids Modulate Autophagy's Proteins in the Hypothalamus
Mariana Portovedo et al.
PLOS ONE (2015)
An Overview of Autophagy: Morphology, Mechanism, and Regulation
Katherine R. Parzych et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis
Kevin W. Williams et al.
CELL METABOLISM (2014)
Hypothalamic Tanycytes Are an ERK-Gated Conduit for Leptin into the Brain
Eglantine Balland et al.
CELL METABOLISM (2014)
Fractalkine (CX3CL1) Is Involved in the Early Activation of Hypothalamic Inflammation in Experimental Obesity
Joseane Morari et al.
DIABETES (2014)
Defective Regulation of the Ubiquitin/Proteasome System in the Hypothalamus of Obese Male Mice
Leticia M. Ignacio-Souza et al.
ENDOCRINOLOGY (2014)
Atypical transforming growth factor-β signaling in the hypothalamus is linked to diabetes
Eliana P. Araujo et al.
NATURE MEDICINE (2014)
Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response
Jingqi Yan et al.
NATURE MEDICINE (2014)
Mitochondrial dynamics in the central regulation of metabolism
Carole M. Nasrallah et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance
Eva Tsaousidou et al.
CELL REPORTS (2014)
Central Ceramide-Induced Hypothalamic Lipotoxicity and ER Stress Regulate Energy Balance
Cristina Contreras et al.
CELL REPORTS (2014)
Mitochondrial Dynamics Controlled by Mitofusins Regulate Agrp Neuronal Activity and Diet-Induced Obesity
Marcelo O. Dietrich et al.
CELL (2013)
Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance
Marc Schneeberger et al.
CELL (2013)
Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing
Isin Cakir et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
Guo Zhang et al.
NATURE (2013)
Loss of Autophagy in Pro-opiomelanocortin Neurons Perturbs Axon Growth and Causes Metabolic Dysregulation
Berengere Coupe et al.
CELL METABOLISM (2012)
Inhibition of Hypothalamic Inflammation Reverses Diet-Induced Insulin Resistance in the Liver
Marciane Milanski et al.
DIABETES (2012)
Loss of autophagy in hypothalamic POMC neurons impairs lipolysis
Susmita Kaushik et al.
EMBO REPORTS (2012)
Obesity is associated with hypothalamic injury in rodents and humans
Joshua P. Thaler et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Targeting the TGFβ signalling pathway in disease
Rosemary J. Akhurst et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance
Susmita Kaushik et al.
CELL METABOLISM (2011)
Partial Reversibility of Hypothalamic Dysfunction and Changes in Brain Activity After Body Mass Reduction in Obese Subjects
Simone van de Sande-Lee et al.
DIABETES (2011)
Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway
Qingyuan Meng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons
Jose Donato et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
Goekhan S. Hotamisligil
CELL (2010)
Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
Lale Ozcan et al.
CELL METABOLISM (2009)
Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents
Stephen C. Benoit et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity
Marciane Milanski et al.
JOURNAL OF NEUROSCIENCE (2009)
RNA granules: post-transcriptional and epigenetic modulators of gene expression
Paul Anderson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Central Administration of an Endoplasmic Reticulum Stress Inducer Inhibits the Anorexigenic Effects of Leptin and Insulin
Jong Chul Won et al.
OBESITY (2009)
High-Fat Diet Induces Apoptosis of Hypothalamic Neurons
Juliana C. Moraes et al.
PLOS ONE (2009)
Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity
Xiaoqing Zhang et al.
CELL (2008)
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
Zane B. Andrews et al.
NATURE (2008)
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
Laura E. Parton et al.
NATURE (2007)
Genetics of obesity in humans
I. Sadaf Farooqi et al.
ENDOCRINE REVIEWS (2006)
Leptin inhibits apoptosis in thymus through a Janus kinase-2-independent, insulin receptor substrate-1/phosphatidylinositol-3 kinase-dependent pathway
Eli Mansour et al.
ENDOCRINOLOGY (2006)
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
CT De Souza et al.
ENDOCRINOLOGY (2005)
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
SH Bates et al.
NATURE (2003)
Role of brain insulin receptor in control of body weight and reproduction
JC Brüning et al.
SCIENCE (2000)
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
E Lien et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
P Ducy et al.
CELL (2000)