Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 16, Pages -Publisher
MDPI
DOI: 10.3390/ijms20163861
Keywords
photodynamic therapy; chlorins; phthalocyanines; porphyrins; skin diseases; skin rejuvenation
Funding
- Sao Paulo Research Foundation (FAPESP) [2018/09088-1, 2018/23015-7, 2017/03552-5]
- Programa de Apoio ao Desenvolvimento Cientifico-Faculdade de Ciencias Farmaceuticas-UNESP (PADC-FCF)
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior - Brasil (CAPES) [001]
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Recent scientific research has shown the use of chlorin, phthalocyanines, and porphyrins derivatives as photosensitizers in photodynamic therapy in the treatment of various pathologies, including some of the major skin diseases. Thus, the main goal of this critical review is to catalog the papers that used these photosensitizers in the treatment of acne vulgaris, psoriasis, papillomavirus infections, cutaneous leishmaniasis, and skin rejuvenation, and to explore the photodynamic therapy mechanisms against these conditions alongside their clinical benefits.
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