Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 19, Pages -Publisher
MDPI
DOI: 10.3390/ijms20194679
Keywords
amoebiasis; mitosome; lipid metabolism; encystation; lateral gene transfer
Funding
- Ministry of Education, Culture, Sports, Science and Technology of Japan [18H04675, 18K07087, 16K08842]
- AMED-J-PRIDE [JP19fm0208025]
- Naito Foundation
- Ohyama Health Foundation Inc.
- Mochida Memorial Foundation
- Takeda Science Foundation
- Grants-in-Aid for Scientific Research [18H04675, 16K08842, 18K07087] Funding Source: KAKEN
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Sulfur metabolism is essential for all living organisms. Recently, unique features of the Entamoeba metabolic pathway for sulfated biomolecules have been described. Entamoeba is a genus in the phylum Amoebozoa and includes the causative agent for amoebiasis, a global public health problem. This review gives an overview of the general features of the synthesis and degradation of sulfated biomolecules, and then highlights the characteristics that are unique to Entamoeba. Future biological and pharmaceutical perspectives are also discussed.
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