Journal
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Volume 41, Issue 12, Pages 4191-4198Publisher
WILEY
DOI: 10.1002/hed.25926
Keywords
ameloblastic carcinoma; diagnosis; odontogenic tumor; pathology; survival
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Funding
- Key Project of the Science and Technology Department of Sichuan Province [2015JY0260]
- National Natural Science Foundation of China [81570974]
- Science and Technology Department of Sichuan Province
- National Natural Science Foundation of China
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Objectives Exploring the clinicopathological features of ameloblastic carcinoma (AC) and reviewing the literature to improve the diagnosis and treatment of the disease. Materials and Methods Clinical data and pathological features of 18 cases of AC were retrospectively analyzed. A systematic review was carried out by searching PubMed and Medline databases using the MeSH terms ameloblastic and carcinoma. Results In the systematic analysis, 125 cases of AC from 81 eligible original studies and 18 cases of AC from this research were included. The male-to-female ratio was 2.58:1, and the mandible-to-maxilla ratio was 1.80:1. Mean age of patients was 45.3 years. Thirty-seven cases of recurrence and 27 cases of metastasis were recorded. Conclusion AC is a rare neoplasm of the odontogenic epithelium. A systematic review indicates that diagnoses at the early phase and a close periodic assessment for recurrence and metastasis are necessary.
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