Journal
FUTURE MEDICINAL CHEMISTRY
Volume 11, Issue 14, Pages 1721-1739Publisher
FUTURE SCI LTD
DOI: 10.4155/fmc-2018-0522
Keywords
antimicrobial photodynamic therapy; aPDT; ICG; indocyanine green; oral biofilm; VIS plus wIRA; visible light and water-filtered infrared A
Categories
Funding
- Swiss Dr. Braun Science Foundation
- German Research Foundation (DFG) [AL 1179/2-1]
Ask authors/readers for more resources
Aim: To investigate the antimicrobial photodynamic therapy (aPDT) of visible light and water-filtered infrared A radiation in combination with indocyanine green (ICG) on planktonic oral microorganisms as well as on oral biofilm. Methods: The irradiation was conducted for 5 min in combination with ICG. Treatment with chlorhexidine served as a positive control. The number of colony forming units and bacterial vitality were quantified. Results: All tested bacterial strains and salivary bacteria were killed at a level of 3log(10). The colony forming units of the initial mature oral biofilms were strongly reduced. The high bactericidal effect of aPDT was confirmed by live/dead staining. Conclusion: The aPDT using visible light and water-filtered infrared A radiation and ICG has the potential to treat periodontitis and peri-implantitis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available