4.5 Article

Strigolactam: New potent strigolactone analogues for the germination of Orobanche cumana

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 25, Issue 10, Pages 2184-2188

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2015.03.056

Keywords

Strigolactones; Orobanche cumana; Seed germination induction; Ketene-iminium salts; Cyclobutanones

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Very recently, strigolactones have been conclusively identified as phytohormones. The progresses achieved in this field are culminating in the identification of the molecular receptors involved in the signal transduction mechanism. The exact mechanism of the mode of action of strigolactones still remains to be fully elucidated and we were interested to gain some insight into the mechanism of action of strigolactones by selectively modifying the reactivity of the lactone C-ring. Therefore, we report here the synthesis of strigolactams 1 and 16 and their surprisingly good activity on the germination of Orobanche cumana parasitic weed seeds. (C) 2015 Elsevier Ltd. All rights reserved.

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