Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2020, Issue 10, Pages 1259-1273Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201901229
Keywords
Dearomatization; Visible light; Arenes; Functionalization; Photochemistry
Categories
Funding
- University of Illinois, Petroleum Research Fund (PRF) [57175-DNI1]
- National Science Foundation [CHE-1654110]
- NIH/National Institute of General Medical Sciences [R01 GM122891]
Ask authors/readers for more resources
The dearomatization of aromatic compounds is an important synthetic strategy used in accessing complex three-dimensional structures from simple aromatic precursors. This minireview aims to provide an overview of recent advancements in this area, with a specific focus on visible-light-mediated dearomative transformations. Compared to the conventional high-energy ultraviolet (UV) light-promoted processes, not only these new approaches offer milder reaction conditions to accommodate wider variety of substrates with sensitive functionalities, but also enable the use of photocatalysts and other promoters, significantly expanding the reaction space. Application of these transformations to the synthesis of bioactive compounds are also discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available