Journal
DERMATITIS
Volume 32, Issue 1S, Pages E80-E82Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/DER.0000000000000512
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This case report describes a 42-year-old woman with severe atopic dermatitis treated with dupilumab developing a reactivation of alopecia areata. Alopecia improved after treatment with intramuscular triamcinolone, raising suspicion of a potential adverse effect of dupilumab in patients with AD.
We present a case report of a 42-year-old woman with severe atopic dermatitis (AD) and history of alopecia areata (AA), which had been in remission for more than 5 years. She was treated with dupilumab for AD, and 4 months after initiating treatment, she developed a rapidly progressive reactivation of AA in an androgenic alopecia pattern. Alopecia resolved after a single intramuscular triamcinolone injection while the patient remained on dupilumab. This is the seventh report to date of dupilumab-associated alopecia but is the first case documenting reactivation of previous AA. Alopecia occurring after dupilumab initiation raises suspicion for a possible unrecognized adverse effect of dupilumab in AD patients.
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