Recent advances of allenes in the first-row transition metals catalyzed C-H activation reactions

Transition-metal-catalyzed C-H activation reaction has proven to be a powerful and efficient tool for the formation of diverse C-C and C-X bond and construction of functional complex molecules. From the viewpoint of sustainable chemistry, the first-row transition metals, such as Mn, Fe, Co, Ni and Cu, have been recognized as cheap, environmentally friendly and reactively effective catalysts for a number of C-H functionalization reactions. However, compared with the commonly used alkenes and alkynes in the first-row transition-metal-catalyzed C-H activations, considerable achievements have just been made by the use of structurally unique and reactively rich allenes as coupling partners in recent years. This review summarizes the recent progress of the first-row transition-metal-catalyzed C-H activations with allenes. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.