4.1 Article

Fluorine-Containing Furan-3(2H)-Ones in Reactions with Binucleophiles: CF3vs C2F5

Journal

CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Volume 55, Issue 6, Pages 517-522

Publisher

SPRINGER
DOI: 10.1007/s10593-019-02488-4

Keywords

4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine; furan-3(2H)-ones; 2-methoxy-2-methyl-5-(perfluoroethyl)furan-3(2H)-one; pyrazole; 1,1,1-trifluoro-3-(2-methylpyrido[2,3-b]pyrazin-3(4H)-ylidene)propan-2-one; N,N- and N,O-binucleophiles

Funding

  1. Russian Foundation for Basic Research [18-33-20124]
  2. Grants Council of the President of the Russian Federation [1453.2019.3]

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Five- and six-membered fluorine-containing azaheterocycles were synthesized based on available furan-3(2H)-ones, and the influence of the nature of the fluoroalkyl substituent on the direction of the chemical transformations by the action of N,N- and N,O-binucleophiles was revealed.

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