4.7 Article

Novel silicon-wollastonite based scaffolds for bone tissue engineering produced by selective laser melting

Journal

CERAMICS INTERNATIONAL
Volume 45, Issue 18, Pages 24691-24701

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.ceramint.2019.08.208

Keywords

Bioceramic; Scaffold; Bioactivity; Additive manufacturing; Selective laser melting

Funding

  1. Estonian Research Council [PUT1063]
  2. Estonian Ministry of Higher Education and Research, Estonia [IUT19-29]
  3. European Regional Fund [2014-2020.4.01.16-0183]
  4. Kristjan Jaak scholarship

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Engineered bone tissue or scaffold is a potential alternative to the common use of bone grafts due to limitless supply and no disease transmission. We present a novel way to manufacture the highly efficient bioceramics combining osteoinductive and bioactive elements using additive manufacturing through selective laser melting without polymer based binder addition and post-processing sintering steps. A formulation of powder feedstock for the production of the scaffolds with an optimized geometry and a high strength is proposed. The structure with circular pores of 400 mu m in diameter and porosity level of 35% exhibits density of around 1.4 g/cm(3) and a compressive strength of 110 MPa, which is only slightly decreased after the immersion into Tris Buffer for two weeks being of 90 MPa. The scaffolds demonstrate a high bioactivity and a controlled growth of the hydroxyapatite-like layer on the surface of the structures. The results of this work illustrate the ability for fabrication of complex-shaped ceramic based structures to be used as novel bone scaffolds and implants by SLM, and the promise for development of other ceramic - based materials using the proper precursor powders feedstock.

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