4.0 Article

1H, 15N backbone assignment and comparative analysis of the wild type and G12C, G12D, G12V mutants of K-Ras bound to GDP at physiological pH

Related references

Note: Only part of the references are listed.
Article Biophysics

NMR 1H,13C, 15N resonance assignment of the G12C mutant of human K-Ras bound to GppNHp

Alok K. Sharma et al.

BIOMOLECULAR NMR ASSIGNMENTS (2019)

Article Biochemistry & Molecular Biology

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Matthew R. Janes et al.

Article Biophysics

1H, 15N and 13C backbone assignments of GDP-bound human H-Ras mutant G12V

Nader Amin et al.

BIOMOLECULAR NMR ASSIGNMENTS (2016)

Review Biotechnology & Applied Microbiology

Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design

Jonathan M. L. Ostrem et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

Article Oncology

Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations

John C. Hunter et al.

MOLECULAR CANCER RESEARCH (2015)

Article Multidisciplinary Sciences

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site

Mohammad T. Mazhab-Jafari et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biophysics

1H, 13C and 15N resonance assignment for the human K-Ras at physiological pH

Uybach Vo et al.

BIOMOLECULAR NMR ASSIGNMENTS (2013)

Article Multidisciplinary Sciences

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

Jonathan M. Ostrem et al.

NATURE (2013)

Article Multidisciplinary Sciences

In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction

Fumi Shima et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

NMR-based functional profiling of RASopathies and oncogenic RAS mutations

Matthew J. Smith et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Physics, Atomic, Molecular & Chemical

Using chemical shift perturbation to characterise ligand binding

Mike P. Williamson

PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (2013)

Review Oncology

A Comprehensive Survey of Ras Mutations in Cancer

Ian A. Prior et al.

CANCER RESEARCH (2012)

Article Biochemistry & Molecular Biology

Analysis of Binding Site Hot Spots on the Surface of Ras GTPase

Greg Buhrman et al.

JOURNAL OF MOLECULAR BIOLOGY (2011)

Article Chemistry, Multidisciplinary

Automated NMR Resonance Assignment of Large Proteins for Protein-Ligand Interaction Studies

Alvar D. Gossert et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Biochemistry & Molecular Biology

The Hypervariable Region of K-Ras4B Is Responsible for Its Specific Interactions with Calmodulin

Sherwin J. Abraham et al.

BIOCHEMISTRY (2009)

Review Cell Biology

Ras oncogenes: split personalities

Antoine E. Karnoub et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Biochemical Research Methods

A set of BEST triple-resonance experiments for time-optimized protein resonance assignment

Ewen Lescop et al.

JOURNAL OF MAGNETIC RESONANCE (2007)

Article Chemistry, Multidisciplinary

Speeding up three-dimensional protein NMR experiments to a few minutes

Paul Schanda et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Article Chemistry, Multidisciplinary

A simple method to predict protein flexibility using secondary chemical shifts

MV Berjanskii et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Review Multidisciplinary Sciences

Signal transduction - The guanine nucleotide-binding switch in three dimensions

IR Vetter et al.

SCIENCE (2001)