4.6 Editorial Material

Detecting Alcohol-Induced Brain Damage Noninvasively Using Diffusion Tensor Imaging

Journal

ACS CHEMICAL NEUROSCIENCE
Volume 10, Issue 10, Pages 4187-4189

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acschemneuro.9b00481

Keywords

Alcohol; brain damage; DTI; diagnostic marker; white matter; gray matter

Funding

  1. European Union [668863]
  2. Ministerio de Economia y Competitividad [BFU2015-64380-C2-1-R]
  3. FEDER funds [BFU2015-64380-C2-1-R, PGC2018-101055-B-I00]
  4. Ministerio de Ciencia Innovacion y Universidades [PGC2018-101055-B-I00]
  5. Deutsche Forschungsgemeinschaft Center Grant [TRR265-B08]
  6. NARSAD Young Investigator Grant [25104]
  7. European Research Council through a Marie Sklodowska-Curie Individual Fellowship [749506]
  8. Marie Curie Actions (MSCA) [749506] Funding Source: Marie Curie Actions (MSCA)

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While alcohol's detrimental effects on the brain are widely acknowledged, diagnostic markers for detection and monitoring alcohol-induced brain damage are lacking. A recent study showed that diffusion tensor imaging can be used to monitor this damage and characterized the progression of the observed changes into early abstinence. Here, we discuss the main findings of that study and highlight current technical limitations which, once addressed, can pave the way to the development of new powerful diagnostic markers for alcohol-induced brain damage.

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